Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TNIP2 and NCOR2
Number of citations of the paper that reports this interaction (PMID
15604093
)
36
Data Source:
BioGRID
(two hybrid)
TNIP2
NCOR2
Gene Name
TNFAIP3 interacting protein 2
nuclear receptor corepressor 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Membrane
Nuclear Matrix
Nuclear Body
Transcriptional Repressor Complex
Molecular Function
Protein Binding
Protein Kinase Binding
Polyubiquitin Binding
DNA Binding
Chromatin Binding
Transcription Corepressor Activity
Notch Binding
Protein Binding
Histone Deacetylase Binding
Protein N-terminus Binding
Biological Process
Transcription, DNA-templated
Apoptotic Process
Inflammatory Response
I-kappaB Kinase/NF-kappaB Signaling
CD40 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Positive Regulation Of Macrophage Activation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Stabilization
Positive Regulation Of B Cell Activation
Interleukin-1-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Negative Regulation Of Endothelial Cell Apoptotic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Transforming Growth Factor Beta Receptor Signaling Pathway
Notch Signaling Pathway
Gene Expression
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Signaling by Interleukins
Cytokine Signaling in Immune system
Interleukin-1 signaling
Loss of Function of TGFBR2 in Cancer
Signaling by NOTCH1 HD Domain Mutants in Cancer
Metabolism of lipids and lipoproteins
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
TGFBR1 LBD Mutants in Cancer
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
Generic Transcription Pathway
Signaling by NOTCH1
Transcriptional regulation of white adipocyte differentiation
Signaling by NOTCH1 in Cancer
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
FBXW7 Mutants and NOTCH1 in Cancer
TGFBR2 MSI Frameshift Mutants in Cancer
Fatty acid, triacylglycerol, and ketone body metabolism
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Chromatin organization
HDACs deacetylate histones
Loss of Function of SMAD2/3 in Cancer
Signaling by NOTCH
TGFBR2 Kinase Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
NOTCH1 Intracellular Domain Regulates Transcription
Chromatin modifying enzymes
Signaling by TGF-beta Receptor Complex in Cancer
Signaling by TGF-beta Receptor Complex
Signaling by NOTCH1 PEST Domain Mutants in Cancer
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Constitutive Signaling by NOTCH1 PEST Domain Mutants
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) (
23648065
)
Cognitive performance (
19734545
)
Protein-Protein Interactions
23 interactors:
APP
CDKN1A
CHUK
EP300
FBXO25
FLNA
IKBKG
MAP3K8
MAPK1
MKNK1
NCOR2
NFKB1
NFKB2
PDCD6IP
PSMD9
REL
RELA
SMARCD1
SRPK2
STK11
TEK
TNFAIP3
UBC
84 interactors:
AHR
AKT1
AP2M1
AR
ARNT
ATXN1
ATXN1L
BCL6
C1D
CBFA2T2
CEBPB
CEP63
CHUK
CIR1
CNOT2
DDX20
E2F1
ESR1
ESR2
FOS
FOXP1
HDAC1
HDAC10
HDAC3
HDAC4
HDAC5
HDAC7
HIST1H4A
HNF4A
INPP5K
IRF5
JUN
MYBL2
MYOD1
NCOA3
NCOA6
NCOR1
NFE2L2
NFKB1
NFKBIA
NFKBIB
NFKBIE
NR1D1
NR1H2
NR1H4
NR1I2
NR2F1
NR2F2
NR3C1
NR4A1
PML
POU2F1
PPARA
PPARD
PPARG
RANBP9
RARA
RARB
RARG
RBPJ
RELA
RUNX1
RUNX1T1
RXRA
RXRG
SAP30
SIN3A
SKIL
SNW1
SP1
SPEN
SRF
STAT5A
STAT5B
SUMO1
TBL1X
THRA
THRB
TNIK
TNIP2
UBE2I
VDR
YWHAE
ZBTB16
Entrez ID
79155
9612
HPRD ID
18207
02910
Ensembl ID
ENSG00000168884
ENSG00000196498
Uniprot IDs
D6RGJ2
Q8NFZ5
C9J0Q5
C9JE98
C9JFD3
Q9Y618
PDB IDs
1KKQ
1R2B
1XC5
2GPV
2L5G
2LTP
2ODD
3R29
3R2A
4A69
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Innate Immune Response
Regulation Of Type I Interferon Production
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Immune System Process
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-dependent Toll-like Receptor Signaling Pathway
Apoptotic Process
Activation Of Innate Immune Response
Positive Regulation Of Type I Interferon Production
Toll-like Receptor 4 Signaling Pathway
Programmed Cell Death
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Cell Death
Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Innate Immune Response
Immune Response-regulating Signaling Pathway
Positive Regulation Of Immune System Process
Toll-like Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Stress
I-kappaB Kinase/NF-kappaB Signaling
Immune Response
Positive Regulation Of Cytokine Production
Regulation Of Cytokine Production
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Defense Response
Antigen Receptor-mediated Signaling Pathway
Regulation Of Innate Immune Response
Signal Transduction
Regulation Of Immune Response
Positive Regulation Of Immune Response
Positive Regulation Of Gene Expression
NIK/NF-kappaB Signaling
Positive Regulation Of Protein Metabolic Process
Signaling
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Gene Expression
Intracellular Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Response To Organic Substance
Hormone-mediated Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
DNA-templated Transcription, Initiation
Biosynthetic Process
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Response To Lipid
Cellular Response To Hormone Stimulus
Cellular Response To Steroid Hormone Stimulus
Response To Lipid
Cellular Response To Organic Cyclic Compound
Anatomical Structure Development
Response To Hormone
System Development
Tagcloud
?
amico
atm
dissect
entered
erg
formalin
fusions
hiseq
illumina
map2k5
maximise
mek5
men1
nbpf10
needle
ngs
opening
pik3cb
qiagen
read
routinely
screen
sections
spop
technologies
templates
tmprrs2
unstained
yielded
Tagcloud (Difference)
?
amico
atm
dissect
entered
erg
formalin
fusions
hiseq
illumina
map2k5
maximise
mek5
men1
nbpf10
needle
ngs
opening
pik3cb
qiagen
read
routinely
screen
sections
spop
technologies
templates
tmprrs2
unstained
yielded
Tagcloud (Intersection)
?