MKRN3 and ENKD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MKRN3	ENKD1
Gene Name		makorin ring finger protein 3	enkurin domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ribonucleoprotein Complex	Cytoplasmic Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 PEX10 PEX5 PRPF31 PSMA1 RBM41 RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W	35 interactors: APP BEGAIN CALCOCO2 CCDC102B CCDC136 CCDC85B CDR2 CEP70 DGCR6 DVL2 DVL3 FAM102A KRTAP10-5 MDFI MIPOL1 MKRN3 NBPF22P NEFL PDLIM7 PHC2 PLSCR1 PNMA1 PNMA2 PPP1CC RAD54B RBPMS SPERT SPSB3 TRAF2 TRGV7 TRIM54 TSC22D4 UBXN11 YWHAE ZBTB14
Entrez ID		7681	84080
HPRD ID		04836	13151
Ensembl ID		ENSG00000179455	ENSG00000124074
Uniprot IDs		Q13064	Q9H0I2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Cellular Response To Stress Catabolic Process Cellular Response To DNA Damage Stimulus Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Ubiquitin-protein Transferase Activity Activation Of Innate Immune Response Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Cellular Response To Hypoxia Positive Regulation Of Innate Immune Response Cellular Response To Decreased Oxygen Levels DNA Repair Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Viral Process	Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAP Kinase Activity Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of Protein Serine/threonine Kinase Activity Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of MAP Kinase Activity Cochlea Morphogenesis Hippo Signaling Non-canonical Wnt Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of Kinase Activity Cochlea Development Positive Regulation Of Protein Kinase Activity Axon Cargo Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Response To Stress Regulation Of Protein Tyrosine Kinase Activity Outflow Tract Morphogenesis Regulation Of Phosphorylation Synaptic Growth At Neuromuscular Junction Regulation Of Heart Rate By Hormone Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Protein Modification Process Regulation Of Binding Positive Regulation Of Transferase Activity Neuromuscular Process Controlling Balance Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Neurofilament Bundle Assembly Collateral Sprouting In Absence Of Injury Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Signaling
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