MKRN3 and TCHP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MKRN3	TCHP
Gene Name		makorin ring finger protein 3	trichoplein, keratin filament binding
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ribonucleoprotein Complex	Cytoplasm Mitochondrion Centrosome Plasma Membrane Keratin Filament Apical Cortex
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination	Apoptotic Process Negative Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS			Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		55 interactors: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 PEX10 PEX5 PRPF31 PSMA1 RBM41 RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W	21 interactors: CCDC172 CCDC85B CDR2 DYDC1 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM
Entrez ID		7681	84260
HPRD ID		04836	14403
Ensembl ID		ENSG00000179455	ENSG00000139437
Uniprot IDs		Q13064	Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Cellular Response To Stress Catabolic Process Cellular Response To DNA Damage Stimulus Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Ubiquitin-protein Transferase Activity Activation Of Innate Immune Response Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Cellular Response To Hypoxia Positive Regulation Of Innate Immune Response Cellular Response To Decreased Oxygen Levels DNA Repair Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Viral Process	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Developmental Process Cytoskeleton Organization Anatomical Structure Development Epidermis Development Hemidesmosome Assembly Epithelium Development Organelle Organization Hepatocyte Apoptotic Process Intermediate Filament Organization Cellular Component Assembly Tumor Necrosis Factor-mediated Signaling Pathway Response To Zinc Ion Cell-substrate Junction Assembly Tissue Development Golgi To Plasma Membrane CFTR Protein Transport Cellular Response To Menadione Negative Regulation Of Interleukin-2 Secretion Organ Development Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Hair Cycle Meiotic Gene Conversion Response To Tumor Necrosis Factor Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Response To Inorganic Substance Negative Regulation Of Calcium Ion Import Male Meiosis Chromosome Segregation Intermediate Filament Bundle Assembly Cell Differentiation Response To Ionizing Radiation Cell Death Death Keratinocyte Migration Negative Regulation Of Transcription From RNA Polymerase III Promoter Epithelial Cell Differentiation Response To Hydrostatic Pressure Bergmann Glial Cell Differentiation Viral Process Interferon-gamma Secretion Chiasma Assembly
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