MKRN3 and UBE2W

Number of citations of the paper that reports this interaction (PubMedID 19549727)
29

Data Source:
BioGRID (two hybrid)

		MKRN3	UBE2W
Description		makorin ring finger protein 3	ubiquitin conjugating enzyme E2 W
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins DNA Damage Response Protein Ubiquitination Cellular Response To Nutrient Levels TORC1 Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein Antiviral Innate Immune Response Negative Regulation Of TORC1 Signaling
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Height ( 31562340) Menarche (age at onset) ( 25231870) Pre-treatment viral load in HIV-1 infection ( 31219150)	Cervical high-risk human papilloma virus infection ( 33225922) Malaria ( 31844061) Manganese levels ( 26025379) Urate levels in obese individuals ( 25811787)
Interacting Genes		181 interacting genes: ACOT11 ADAMTSL4 ADRA2C ANKRD11 ANTKMT APEX2 AQP1 ARID5A ARMC5 ATOSB AVPI1 BATF2 BCL2L11 BEX2 BLZF1 BPIFA1 C21orf58 CCDC120 CCDC185 CCDC187 CCDC33 CDCA4 CEP70 CERCAM CIMAP1B CRACR2A CYSRT1 DDIT4L ECM1 ECSIT EFEMP1 ENKD1 ERCC1 FAM110A FAM124B FARS2 GADD45GIP1 GATA1 GEM GOLGA6A GRAP2 HCK HGS HOXA1 HOXD12 HSF2BP HSF4 IGF1 IKZF3 INO80B KANK2 KIF1A KIFC3 KLF1 KLHL38 KRT34 KRT75 KRT86 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP6-2 KRTAP7-1 KRTAP8-1 LAGE3 LASP1 LRSAM1 MAGED1 MBD3 MCCD1 MDM2 MDM4 MEOX1 MEOX2 MGAT5B MIF4GD MNAT1 MORN3 MRPL38 MRPS6 MYOZ2 NABP1 NDE1 NDUFB7 NKAPD1 NME4 ODAD4 PABPC4 PEX10 PEX5 PKN1 POLR1C POMC PRKAA2 PRPF31 PRR22 PRR35 PSMA1 PSMB1 PTH1R PTK6 RASD1 RBM41 RBPMS RBPMS2 RIBC1 RNF10 RNF166 RNF32 RNF7 RSPH1 RSPO4 RTP5 SCNM1 SF1 SFN SLPI SMARCD1 SMYD3 SNRPC SORBS3 SPATA8 SPMIP5 STH STMN3 STN1 SYNGAP1 TADA2A TASOR2 TCEA2 TCHP TCL1B TENT5B TFAP2A TFIP11 TLE5 TPRX1 TRAF2 TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TSGA10IP TSPAN4 TTC23 TXNDC11 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W UQCC2 USHBP1 VPS9D1 WDR25 WWOX YPEL3 ZBTB42 ZFC3H1 ZFP57 ZIM2 ZNF34 ZNF414 ZNF587 ZNF688 ZNF835	81 interacting genes: AKR1C3 AMFR ARK2C ATXN3 BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CBL CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED FANCL LRSAM1 MAP3K1 MAPT MARCHF3 MARCHF5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF166 RNF167 RNF183 RNF185 RNF2 RNF26 RNF31 RNF4 RNF5 RNF8 ROPN1 SNCA STUB1 TOPORS TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM3 TRIM31 TRIM35 TRIM39 TRIM5 TRIM59 TRIM7 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID		7681	55284
HPRD ID		04836	07724
Ensembl ID		ENSG00000179455	ENSG00000104343
Uniprot IDs		Q13064	Q96B02 Q96FI0 X6REH9
PDB IDs			2A7L 2MT6 8A58
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Binding Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein K63-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Modification-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Protein K48-linked Ubiquitination Regulation Of Nucleobase-containing Compound Metabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription UBC13-MMS2 Complex Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Activity Nucleus Protein Modification Process Ubiquitin Conjugating Enzyme Complex Intermediate Filament Macromolecule Catabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Protein Polyubiquitination Transferase Activity Positive Regulation Of Protein K63-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Regulation Of Gene Expression Zinc Ion Binding Error-free Postreplication DNA Repair Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Regulation Of Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity Regulation Of Protein K63-linked Ubiquitination Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Proteasomal Protein Catabolic Process TORC1 Signaling NEDD8 Ligase Activity ISG15 Transferase Activity	Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Modification Process Transferase Activity Zinc Ion Binding Protein Metabolic Process Metal Ion Binding Macromolecule Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Protein Autoubiquitination Proteolysis Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Catabolic Process Response To Stress Proteasomal Protein Catabolic Process Cellular Response To Stress Protein K6-linked Ubiquitination Ubiquitin Ligase Complex Regulation Of Intracellular Signal Transduction Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Signal Transduction Cytoplasm Canonical NF-kappaB Signal Transduction Suppression Of Viral Release By Host Positive Regulation Of Catabolic Process Innate Immune Response Immune System Process DNA Damage Response Positive Regulation Of Autophagy Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Response To Other Organism Regulation Of Autophagy Regulation Of Signaling Regulation Of Cell Communication Regulation Of Defense Response Defense Response To Symbiont Endoplasmic Reticulum Mannose Trimming Intracellular Signal Transduction Defense Response To Other Organism Response To External Biotic Stimulus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?