MKRN3 and FAM124B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MKRN3	FAM124B
Gene Name		makorin ring finger protein 3	family with sequence similarity 124B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ribonucleoprotein Complex
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 PEX10 PEX5 PRPF31 PSMA1 RBM41 RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W	29 interactors: ADAMTSL4 AES BIRC7 CARD9 CCDC85B EFEMP2 GOLGA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MDFI MKRN3 NOTCH2NL RBPMS RINT1 SSX2IP TCF4 TRIM37 TRIM54 TRIP6 USHBP1
Entrez ID		7681	79843
HPRD ID		04836	08663
Ensembl ID		ENSG00000179455	ENSG00000124019
Uniprot IDs		Q13064	Q9H5Z6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Cellular Response To Stress Catabolic Process Cellular Response To DNA Damage Stimulus Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Ubiquitin-protein Transferase Activity Activation Of Innate Immune Response Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Cellular Response To Hypoxia Positive Regulation Of Innate Immune Response Cellular Response To Decreased Oxygen Levels DNA Repair Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Viral Process	Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Transport Regulation Of Binding Regulation Of Intracellular Protein Transport Negative Regulation Of Binding Regulation Of Signal Transduction Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Wnt Signaling Pathway Positive Regulation Of JNK Cascade Cellular Component Assembly Regulation Of Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Cellular Localization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Intracellular Protein Transport Regulation Of JNK Cascade Activation Of JUN Kinase Activity Regulation Of Protein Import Into Nucleus Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Natural Killer Cell Apoptotic Process Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Positive Regulation Of Intracellular Transport Negative Regulation Of Fat Cell Differentiation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of JUN Kinase Activity Wnt Signaling Pathway Regulation Of Protein Transport Negative Regulation Of Protein Localization To Nucleus Regulation Of JUN Kinase Activity Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination JNK Cascade Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription Factor Import Into Nucleus Regulation Of Establishment Of Protein Localization Negative Regulation Of RNA Biosynthetic Process Maintenance Of DNA Repeat Elements
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