MKRN3 and PRPF31

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MKRN3	PRPF31
Gene Name		makorin ring finger protein 3	pre-mRNA processing factor 31
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ribonucleoprotein Complex	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding
	Biological Process	Protein Ubiquitination	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 PEX10 PEX5 PRPF31 PSMA1 RBM41 RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W	55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587
Entrez ID		7681	26121
HPRD ID		04836	05917
Ensembl ID		ENSG00000179455	ENSG00000105618
Uniprot IDs		Q13064	E7ESA8 F1T0A4 F1T0A5 Q8WWY3
PDB IDs			2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Cellular Response To Stress Catabolic Process Cellular Response To DNA Damage Stimulus Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Ubiquitin-protein Transferase Activity Activation Of Innate Immune Response Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Cellular Response To Hypoxia Positive Regulation Of Innate Immune Response Cellular Response To Decreased Oxygen Levels DNA Repair Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Viral Process	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly
Tagcloud ?			ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Difference) ?			ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Intersection) ?