UBE2W and RNF14

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		UBE2W	RNF14
Gene Name		ubiquitin-conjugating enzyme E2W (putative)	ring finger protein 14
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Androgen Receptor Binding
	Biological Process	DNA Repair Protein Monoubiquitination Misfolded Or Incompletely Synthesized Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Protein Ubiquitination Androgen Receptor Signaling Pathway Response To Estradiol Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		69 interactors: AKR1C3 AMFR BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED FANCL LRSAM1 MAP3K1 MARCH3 MARCH5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF185 RNF2 RNF26 RNF4 RNF5 RNF8 ROPN1 STUB1 TOPORS TRIM17 TRIM2 TRIM27 TRIM31 TRIM35 TRIM39 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF4	22 interactors: AR DACH1 ESR1 FAM46A HNF1A HNRNPA1 NCOA4 NR3C1 PHF7 TAGLN TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2U UBE2V1 UBE2W VDR
Entrez ID		55284	9604
HPRD ID		07724	05745
Ensembl ID		ENSG00000104343	ENSG00000013561
Uniprot IDs		Q96B02 Q96FI0	B7Z229 Q9UBS8
PDB IDs		2A7L
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Metabolic Process Protein Autoubiquitination Cellular Metabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Metabolic Process Cellular Response To Stress Catabolic Process Protein Monoubiquitination Response To Stress Cellular Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Viral Release From Host Cell Proteasomal Protein Catabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell DNA Repair Negative Regulation Of Viral Transcription Proteolysis Apoptotic Process Regulation Of Gene Expression By Genetic Imprinting Regulation Of Viral Transcription Programmed Cell Death Negative Regulation Of Viral Process Regulation Of Viral Process Cell Death Death Positive Regulation Of Organelle Organization Genetic Imprinting Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Histone Methylation Histone Ubiquitination Cellular Response To Stimulus	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Steroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Response To Organic Substance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Hormone-mediated Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Protein Monoubiquitination Cellular Protein Catabolic Process Mammary Gland Branching Involved In Pregnancy Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Catabolic Process Cellular Response To Organic Substance Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress ISG15-protein Conjugation Regulation Of DNA-templated Transcription In Response To Stress Mammary Gland Duct Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Lipid TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Protein Modification Process Cellular Response To Stress Developmental Process Involved In Reproduction MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		advance amines chemically cleave cleaving deubiquitylating displaying dub dubs fusions homopolymers hydrolase isopeptide k11 l3 linkage linkages mono monoubiquitylation preference reversal striking sumo2 synthesised topologically ubiquitylation uch unstructured
Tagcloud (Difference) ?		advance amines chemically cleave cleaving deubiquitylating displaying dub dubs fusions homopolymers hydrolase isopeptide k11 l3 linkage linkages mono monoubiquitylation preference reversal striking sumo2 synthesised topologically ubiquitylation uch unstructured
Tagcloud (Intersection) ?