UBE2W and RNF123

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		UBE2W	RNF123
Gene Name		ubiquitin-conjugating enzyme E2W (putative)	ring finger protein 123
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Zinc Ion Binding Ligase Activity
	Biological Process	DNA Repair Protein Monoubiquitination Misfolded Or Incompletely Synthesized Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		69 interactors: AKR1C3 AMFR BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED FANCL LRSAM1 MAP3K1 MARCH3 MARCH5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF185 RNF2 RNF26 RNF4 RNF5 RNF8 ROPN1 STUB1 TOPORS TRIM17 TRIM2 TRIM27 TRIM31 TRIM35 TRIM39 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF4	5 interactors: CDKN1B SMAD2 SMAD9 UBAC1 UBE2W
Entrez ID		55284	63891
HPRD ID		07724	11499
Ensembl ID		ENSG00000104343	ENSG00000164068
Uniprot IDs		Q96B02 Q96FI0	C9JS59 Q5XPI4
PDB IDs		2A7L	2MA6
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Metabolic Process Protein Autoubiquitination Cellular Metabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Metabolic Process Cellular Response To Stress Catabolic Process Protein Monoubiquitination Response To Stress Cellular Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Viral Release From Host Cell Proteasomal Protein Catabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell DNA Repair Negative Regulation Of Viral Transcription Proteolysis Apoptotic Process Regulation Of Gene Expression By Genetic Imprinting Regulation Of Viral Transcription Programmed Cell Death Negative Regulation Of Viral Process Regulation Of Viral Process Cell Death Death Positive Regulation Of Organelle Organization Genetic Imprinting Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Histone Methylation Histone Ubiquitination Cellular Response To Stimulus	Cellular Response To Organic Cyclic Compound Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Organic Substance Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Response To Glucose Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Kidney Epithelium Development Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Carbohydrate Response To Organic Substance Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Response To Transforming Growth Factor Beta Protein Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Mesoderm Development Primary MiRNA Processing Autophagic Cell Death Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Response To Hypoxia Positive Regulation Of Activin Receptor Signaling Pathway Mullerian Duct Regression Cellular Protein Modification Process Kidney Development Renal System Development SMAD Protein Complex Assembly Urogenital System Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Paraxial Mesoderm Morphogenesis Positive Regulation Of Microtubule Polymerization Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Nodal Signaling Pathway Mitotic Cell Cycle Arrest Response To Misfolded Protein Cellular Response To Lithium Ion Anatomical Structure Regression Cellular Response To Antibiotic Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Intracellular Signal Transduction Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis
Tagcloud ?		advance amines chemically cleave cleaving deubiquitylating displaying dub dubs fusions homopolymers hydrolase isopeptide k11 l3 linkage linkages mono monoubiquitylation preference reversal striking sumo2 synthesised topologically ubiquitylation uch unstructured
Tagcloud (Difference) ?		advance amines chemically cleave cleaving deubiquitylating displaying dub dubs fusions homopolymers hydrolase isopeptide k11 l3 linkage linkages mono monoubiquitylation preference reversal striking sumo2 synthesised topologically ubiquitylation uch unstructured
Tagcloud (Intersection) ?