UBE2W and MKRN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		UBE2W	MKRN1
Gene Name		ubiquitin-conjugating enzyme E2W (putative)	makorin ring finger protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cellular_component
	Molecular Function	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding
	Biological Process	DNA Repair Protein Monoubiquitination Misfolded Or Incompletely Synthesized Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein	Protein Polyubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		69 interactors: AKR1C3 AMFR BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED FANCL LRSAM1 MAP3K1 MARCH3 MARCH5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF185 RNF2 RNF26 RNF4 RNF5 RNF8 ROPN1 STUB1 TOPORS TRIM17 TRIM2 TRIM27 TRIM31 TRIM35 TRIM39 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF4	7 interactors: CSNK1G1 DUSP23 EXOSC8 FADD MAP1LC3B UBE2D3 UBE2W
Entrez ID		55284	23608
HPRD ID		07724	09673
Ensembl ID		ENSG00000104343	ENSG00000133606
Uniprot IDs		Q96B02 Q96FI0	Q9UHC7
PDB IDs		2A7L
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Protein Metabolic Process Protein Autoubiquitination Cellular Metabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Metabolic Process Cellular Response To Stress Catabolic Process Protein Monoubiquitination Response To Stress Cellular Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Viral Release From Host Cell Proteasomal Protein Catabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell DNA Repair Negative Regulation Of Viral Transcription Proteolysis Apoptotic Process Regulation Of Gene Expression By Genetic Imprinting Regulation Of Viral Transcription Programmed Cell Death Negative Regulation Of Viral Process Regulation Of Viral Process Cell Death Death Positive Regulation Of Organelle Organization Genetic Imprinting Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Histone Methylation Histone Ubiquitination Cellular Response To Stimulus	Protein K11-linked Ubiquitination Protein Monoubiquitination TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Toll-like Receptor Signaling Pathway Motor Neuron Apoptotic Process Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRAIL-activated Apoptotic Signaling Pathway Catabolic Process Protein Polyubiquitination Positive Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Necroptotic Signaling Pathway Positive Regulation Of Cellular Extravasation Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Macrophage Differentiation Negative Regulation Of Activation-induced Cell Death Of T Cells Positive Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Activation-induced Cell Death Of T Cells Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Negative Regulation Of Necroptotic Process Response To Misfolded Protein Cellular Response To Nitrogen Starvation Lymph Node Development Negative Regulation Of Necrotic Cell Death Regulation Of Necroptotic Process Positive Regulation Of T Cell Migration Regulation Of T Cell Migration Nucleophagy Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Activated T Cell Proliferation Regulation Of Necrotic Cell Death Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Stress Immune Response-regulating Signaling Pathway Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Protein Modification Process Negative Regulation Of T Cell Apoptotic Process Mitochondrion Degradation
Tagcloud ?		advance amines chemically cleave cleaving deubiquitylating displaying dub dubs fusions homopolymers hydrolase isopeptide k11 l3 linkage linkages mono monoubiquitylation preference reversal striking sumo2 synthesised topologically ubiquitylation uch unstructured	apathogenic aspects cap circovirus gc1qr genotypes hsp40 hybrid immunofluorescence interacting lifecycle localisation nap1 npm1 others overlapping par pathogen pcv pcv1 pcv2 porcine prominent redistribution rep swine tdg vg5q znf265
Tagcloud (Difference) ?		advance amines chemically cleave cleaving deubiquitylating displaying dub dubs fusions homopolymers hydrolase isopeptide k11 l3 linkage linkages mono monoubiquitylation preference reversal striking sumo2 synthesised topologically ubiquitylation uch unstructured	apathogenic aspects cap circovirus gc1qr genotypes hsp40 hybrid immunofluorescence interacting lifecycle localisation nap1 npm1 others overlapping par pathogen pcv pcv1 pcv2 porcine prominent redistribution rep swine tdg vg5q znf265
Tagcloud (Intersection) ?