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RAD51D and CEP57L1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid)
RAD51D
CEP57L1
Description
RAD51 paralog D
centrosomal protein 57 like 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Chromosome
Cytoplasm
Centrosome
Microtubule Organizing Center
Cytoskeleton
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Cytoplasm
Centrosome
Cytoskeleton
Microtubule
Molecular Function
Nucleotide Binding
Four-way Junction DNA Binding
DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
ATP-dependent Activity, Acting On DNA
Gamma-tubulin Binding
ATP-dependent DNA Damage Sensor Activity
Protein Binding
Microtubule Binding
Identical Protein Binding
Gamma-tubulin Binding
Biological Process
Telomere Maintenance Via Recombination
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Repair
DNA Recombination
DNA Damage Response
Reciprocal Meiotic Recombination
Interstrand Cross-link Repair
DNA Strand Invasion
Chromosome Organization
Regulation Of Cell Cycle
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
Defective homologous recombination repair (HRR) due to BRCA1 loss of function
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Impaired BRCA2 binding to PALB2
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Midgestational circulating levels of PCBs (
28235828
)
Prostate cancer (
23535732
)
Interacting Genes
49 interacting genes:
AMOTL2
BLM
C1orf94
CCDC33
CCNL1
CEP57L1
EFHC2
GEMIN4
HSF2BP
IHO1
IKZF1
IKZF3
KATNBL1
KIFC3
KRT15
LIMS1
LNX1
LZTS2
MAPK8IP3
MEOX2
NFKBID
PICK1
PNMA1
POLDIP3
PRDM14
PRDM6
RAD51B
RAD51C
RBM48
REL
RHOU
RNF138
SORBS3
SPATC1L
STX11
SWSAP1
TCF4
TEPSIN
TLE5
TRIM14
TTC23
VPS9D1
XRCC2
XRCC3
ZBTB42
ZC2HC1C
ZNF343
ZNF774
ZSWIM7
85 interacting genes:
AKT1
ALOX5
AP1M1
ARNT2
BRCA1
BYSL
CALCOCO2
CARD9
CBY2
CCDC102B
CCDC136
CCDC57
CDR2
CEP44
CEP55
CEP63
CEP70
CFAP206
DISC1
DVL3
DYDC1
ELOA
EXOC8
FAM161A
FAM9B
GADD45G
GOLGA1
GOLGA2
GRIPAP1
HAUS1
HDDC3
HGS
IKZF1
KATNAL1
KIFC3
KLC3
KLC4
KRT13
KRT19
KRT31
KRT38
KRT40
LCOR
LENG1
LMO1
LMO3
LZTS2
MAGEA1
MAGEA2B
MCC
MDFI
MEOX2
MFAP1
MID2
MORF4L1
MTUS2
MYO15B
NEFL
NOTCH1
NUP62
PATJ
PICK1
PKN1
PNMA5
PPL
PRDM6
RAD51D
RINT1
ROPN1
SNAP47
SNAPC3
TAB3
TFIP11
TRAF2
TRAPPC2L
TRIM54
TRIP6
TSGA10
TXLNA
TXLNB
VPS28
YES1
ZGPAT
ZNF572
ZNF655
Entrez ID
5892
285753
HPRD ID
04261
10792
Ensembl ID
ENSG00000185379
ENSG00000183137
Uniprot IDs
O75771
E5RFY4
E5RJH1
Q6P2R3
Q8IYX8
PDB IDs
2KZ3
8FAZ
8GBJ
8OUY
8OUZ
Enriched GO Terms of Interacting Partners
?
Four-way Junction DNA Binding
Recombinational Repair
Double-strand Break Repair Via Homologous Recombination
Double-strand Break Repair
Replication Fork
DNA Recombination
Rad51B-Rad51C-Rad51D-XRCC2 Complex
ATP-dependent DNA Damage Sensor Activity
Protein Binding
Rad51C-XRCC3 Complex
Shu Complex
DNA Repair
DNA Metabolic Process
DNA Binding
Resolution Of DNA Recombination Intermediates
Single-stranded DNA Binding
Crossover Junction DNA Endonuclease Activity
DNA Damage Response
Telomeric Loop Disassembly
T-circle Formation
Telomere Maintenance Via Recombination
Zinc Ion Binding
Somite Development
Meiosis I Cell Cycle Process
Cytoskeleton
Protein Binding
Cytoplasm
Organelle Organization
Centrosome
Microtubule Organizing Center Organization
Microtubule-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Microtubule
Intermediate Filament Organization
Centrosome Cycle
Microtubule Binding
Identical Protein Binding
Organelle Assembly
Structural Constituent Of Skin Epidermis
Intermediate Filament
Centriole Assembly
Centriole
Kinesin Complex
Cytoskeleton Organization
Keratin Filament
Syntaxin Binding
Spindle Pole
Cellular Component Assembly
Centriole Replication
Structural Molecule Activity
Microtubule Cytoskeleton Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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