XPC and LSM3

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		XPC	LSM3
Gene Name		xeroderma pigmentosum, complementation group C	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Extracellular Vesicular Exosome XPC Complex	Nucleus Cytosol Catalytic Step 2 Spliceosome
	Molecular Function	Heteroduplex DNA Loop Binding Bubble DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Response To UV-B Intra-S DNA Damage Checkpoint Response To Drug Regulation Of Mitotic Cell Cycle Phase Transition	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome MRNA Processing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER DNA Damage Recognition in GG-NER Dual incision reaction in GG-NER	mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ABCA1 CETN2 DDB2 ERCC3 GTF2H1 LSM3 MDM2 PSMD4 RAD23A RAD23B RPA1 SMAD1 SUMO2 TDG USP7 ZNF512B	28 interactors: CEP95 CLNS1A DLX4 EEF1A1 GDF9 GSTA1 KEAP1 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 SF3B2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1
Entrez ID		7508	27258
HPRD ID		02046	06283
Ensembl ID		ENSG00000154767
Uniprot IDs		Q01831	P62310
PDB IDs		2A4J 2GGM 2OBH
Enriched GO Terms of Interacting Partners?		Nucleotide-excision Repair Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Nucleotide-excision Repair, DNA Damage Removal DNA Repair Cellular Response To Stress DNA Catabolic Process Catabolic Process Response To Stress DNA Metabolic Process Aromatic Compound Catabolic Process Transcription-coupled Nucleotide-excision Repair Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Viral Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Proteolysis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Cellular Protein Metabolic Process Cellular Response To Stimulus Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Catabolic Process Chromosome Organization Protein Catabolic Process Cellular Protein Modification Process Response To UV Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Protein Metabolic Process Termination Of RNA Polymerase I Transcription Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Viral Process Transcription Elongation From RNA Polymerase I Promoter Regulation Of Cellular Protein Metabolic Process Response To Stimulus Transcription Initiation From RNA Polymerase I Promoter Metabolic Process 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Regulation Of Cell Cycle Process	MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Ribonucleoprotein Complex Assembly NcRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination RNA Catabolic Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Catabolic Process Spliceosomal Complex Assembly MRNA Catabolic Process MRNA 3'-end Processing Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly RNA 3'-end Processing Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Catabolic Process Maturation Of SSU-rRNA Transcription, DNA-templated RNA Biosynthetic Process Ribosomal Small Subunit Biogenesis Oocyte Growth Nucleotide-excision Repair, DNA Damage Recognition Cellular Component Assembly Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Progesterone Secretion Proteasomal Ubiquitin-independent Protein Catabolic Process CRD-mediated MRNA Stabilization
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