XPC

Gene Name		xeroderma pigmentosum, complementation group C
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Extracellular Vesicular Exosome XPC Complex
	Molecular Function	Heteroduplex DNA Loop Binding Bubble DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Response To UV-B Intra-S DNA Damage Checkpoint Response To Drug Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER DNA Damage Recognition in GG-NER Dual incision reaction in GG-NER
Drugs
Diseases
GWAS
Protein-protein Interactions		16 interactors: ABCA1 CETN2 DDB2 ERCC3 GTF2H1 LSM3 MDM2 PSMD4 RAD23A RAD23B RPA1 SMAD1 SUMO2 TDG USP7 ZNF512B
Entrez ID		7508
HPRD ID		02046
Ensembl ID		ENSG00000154767
Uniprot IDs		Q01831
PDB IDs		2A4J 2GGM 2OBH
Enriched GO Terms of Interacting Partners?		Nucleotide-excision Repair Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Nucleotide-excision Repair, DNA Damage Removal DNA Repair Cellular Response To Stress DNA Catabolic Process Catabolic Process Response To Stress DNA Metabolic Process Aromatic Compound Catabolic Process Transcription-coupled Nucleotide-excision Repair Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Viral Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Proteolysis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Cellular Protein Metabolic Process Cellular Response To Stimulus Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Catabolic Process Chromosome Organization Protein Catabolic Process Cellular Protein Modification Process Response To UV Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Protein Metabolic Process Termination Of RNA Polymerase I Transcription Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Viral Process Transcription Elongation From RNA Polymerase I Promoter Regulation Of Cellular Protein Metabolic Process Response To Stimulus Transcription Initiation From RNA Polymerase I Promoter Metabolic Process 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Regulation Of Cell Cycle Process
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