TM4SF19 and GIMAP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		TM4SF19	GIMAP5
Description		transmembrane 4 L six family member 19	GTPase, IMAP family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Cytoskeleton Actin Cytoskeleton Membrane Filopodium Cell Projection	Lysosome Lysosomal Membrane Endosome Endosome Membrane Membrane Multivesicular Body Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Positive Regulation Of Osteoclast Differentiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: ABHD16A ARLN ATP6V0B BNIP1 C14orf180 CCDC167 CD79A CRK CTXN3 CYBC1 CYP4F2 DAPP1 ERG28 GET1 GIMAP1 GIMAP5 GOSR2 GPR152 HMOX1 NDUFA3 PLP2 PMP22 RIN3 SEC22B SERP2 SMIM1 STAT3 STX7 SYS1 TMEM167B TMEM179B TMEM237 TMEM42 TNS2 TSNARE1 UBE2J1 VAMP3 VAMP4 ZFPL1	68 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM209A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GPR42 GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC10A6 SLC35H1 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZER1 ZFYVE27
Entrez ID		116211	55340
HPRD ID		14013	16280
Ensembl ID		ENSG00000145107	ENSG00000196329
Uniprot IDs		B7ZW46 Q96DZ7	A0A090N8P9 Q96F15
PDB IDs			6Z3E
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Organelle Fusion Membrane Fusion Organelle Membrane Fusion Endoplasmic Reticulum Vesicle-mediated Transport Golgi Vesicle Transport Vesicle Fusion Golgi To Plasma Membrane Protein Transport Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Vesicle Docking SNARE Complex Assembly Golgi To Plasma Membrane Transport SNARE Binding Golgi Membrane Endocytic Vesicle Membrane Organization Vesicle Organization Organelle Localization By Membrane Tethering Phagocytic Vesicle Membrane Protein Binding Membrane Docking	Membrane Protein Binding Exocytosis Plasma Membrane Endoplasmic Reticulum Membrane Secretion By Cell Identical Protein Binding Ascorbate Homeostasis Secretion Positive Regulation Of Regulated Secretory Pathway Regulated Exocytosis Glutathione Peroxidase Activity Transmembrane Monodehydroascorbate Reductase Activity Endomembrane System Vesicle Docking Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site SNARE Binding Tertiary Granule Membrane Leukotriene-C4 Synthase Activity Bile Acid:sodium Symporter Activity Vesicle-mediated Transport Glutathione Transferase Activity Cornified Envelope Assembly Endoplasmic Reticulum Organelle Localization By Membrane Tethering Calcium-ion Regulated Exocytosis Specific Granule Membrane Positive Regulation Of Exocytosis Renal Water Transport Chromaffin Granule Membrane Membrane Docking SNAP Receptor Activity Disulfide Oxidoreductase Activity Vesicle Fusion Glutathione Binding Icosanoid Biosynthetic Process Tumor Necrosis Factor Receptor Activity Nuclear Envelope Lumen SNARE Complex Organelle Membrane Fusion Positive Regulation Of Catecholamine Secretion SNARE Complex Assembly
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