TM4SF19 and SYS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		TM4SF19	SYS1
Description		transmembrane 4 L six family member 19	SYS1 golgi trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Cytoskeleton Actin Cytoskeleton Membrane Filopodium Cell Projection	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Positive Regulation Of Osteoclast Differentiation	Golgi To Endosome Transport Protein Transport Protein Localization To Golgi Apparatus Golgi To Plasma Membrane Protein Transport
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Free cholesterol levels in large HDL ( 29084231) Large HDL particle concentration ( 29084231) Malaria ( 31844061) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231)
Interacting Genes		39 interacting genes: ABHD16A ARLN ATP6V0B BNIP1 C14orf180 CCDC167 CD79A CRK CTXN3 CYBC1 CYP4F2 DAPP1 ERG28 GET1 GIMAP1 GIMAP5 GOSR2 GPR152 HMOX1 NDUFA3 PLP2 PMP22 RIN3 SEC22B SERP2 SMIM1 STAT3 STX7 SYS1 TMEM167B TMEM179B TMEM237 TMEM42 TNS2 TSNARE1 UBE2J1 VAMP3 VAMP4 ZFPL1	20 interacting genes: BTNL9 EBP ELOVL5 ERGIC3 FCER1G GLP1R HSD17B11 IL3RA KIR3DL3 MCFD2 MGST3 MRPS18B PSCA PVR SDCBP SLC30A8 SLC35H1 TM4SF19 TMEM248 TNFSF14
Entrez ID		116211	90196
HPRD ID		14013
Ensembl ID		ENSG00000145107	ENSG00000204070
Uniprot IDs		B7ZW46 Q96DZ7	Q8N2H4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Organelle Fusion Membrane Fusion Organelle Membrane Fusion Endoplasmic Reticulum Vesicle-mediated Transport Golgi Vesicle Transport Vesicle Fusion Golgi To Plasma Membrane Protein Transport Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Vesicle Docking SNARE Complex Assembly Golgi To Plasma Membrane Transport SNARE Binding Golgi Membrane Endocytic Vesicle Membrane Organization Vesicle Organization Organelle Localization By Membrane Tethering Phagocytic Vesicle Membrane Protein Binding Membrane Docking	Interleukin-3-mediated Signaling Pathway Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
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