RAB8B and TUBA4A

Number of citations of the paper that reports this interaction (PubMedID 12639940)
0

Data Source:
HPRD (in vivo)

		RAB8B	TUBA4A
Description		RAB8B, member RAS oncogene family	tubulin alpha 4a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Endosome Membrane Membrane Trans-Golgi Network Transport Vesicle Phagocytic Vesicle Membrane Cytoplasmic Vesicle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Presynapse	Extracellular Region Cytoplasm Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Hydrolase Activity GDP Binding TPR Domain Binding Metal Ion Binding	Nucleotide Binding Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Hydrolase Activity Enzyme Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Exocytosis Protein Transport Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Endocytic Recycling Protein Import Into Peroxisome Membrane Positive Regulation Of Corticotropin Secretion Cilium Assembly Cell-substrate Junction Organization	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Platelet degranulation Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Anchoring of the basal body to the plasma membrane Cargo trafficking to the periciliary membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling
Drugs		Phosphoaminophosphonic acid guanylate ester Guanosine-5'-Diphosphate	Vincristine Podofilox Epothilone D Patupilone CYT997 Cabazitaxel Phenethyl Isothiocyanate
Diseases
GWAS		Refractive error ( 32231278) Serum metabolite levels ( 23093944) Social communication problems ( 24564958)	Platelet distribution width ( 27863252 32888494) Severe autoimmune type 2 diabetes ( 34737425)
Interacting Genes		7 interacting genes: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM	53 interacting genes: APC ARHGAP1 B4GALT1 BCAR1 BRCA1 C4orf17 CALB2 EGFR ENO2 EPB41 FYN GNAI2 GPHN GRM7 HDAC6 HSPH1 LGALS2 LTA MAGED1 MAP1A MAP1LC3A MAPT MARK4 MYC NCALD OGT PFDN4 PLK1 PRKN RAB8B RAC1 RACGAP1 RBM23 RTN4 S100A8 SIAH1 SIMC1 SIRT2 STARD13 SUMO2 SYK TAOK2 TBCB TBCE TCP1 TCP11L2 TM4SF1 UBC UCHL5 VAV1 VDAC1 YWHAG ZAP70
Entrez ID		51762	7277
HPRD ID		11476	01851
Ensembl ID		ENSG00000166128	ENSG00000127824
Uniprot IDs		Q92930	P68366
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Extracellular Exosome Cellular Localization Nuclear Envelope Lumen GTPase Activating Protein Binding Structural Constituent Of Cytoskeleton Negative Regulation Of Cell Projection Organization Regulation Of Cellular Component Organization Regulation Of Filopodium Assembly Amyloid-beta Complex Growth Cone Lamellipodium Synaptic Membrane Plasma Membrane Bounded Cell Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glial Cell Development GTP Binding Regulation Of Receptor Internalization Cell Body Acetylcholine Receptor Activator Activity Lipoprotein Particle Cell Projection Organization Positive Regulation Of Protein Import Edg-2 Lysophosphatidic Acid Receptor Binding Dense Core Granule Membrane Negative Regulation Of Type 2 Mitophagy Ciliary Basal Body-plasma Membrane Docking PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Neuron Projection Development Regulation Of Receptor-mediated Endocytosis Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Vesicle-mediated Transport Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Neuron Projection Development Post-Golgi Vesicle-mediated Transport Localization Within Membrane Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Response To External Biotic Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling	Alpha-tubulin Binding Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Microtubule Cytosol Negative Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Apoptotic Process Ubiquitin Protein Ligase Binding Regulation Of Cellular Component Organization Regulation Of Protein Localization Regulation Of Apoptotic Process Positive Regulation Of Protein Localization Plasma Membrane Tubulin Binding Regulation Of Protein Catabolic Process Dendrite Positive Regulation Of Intracellular Signal Transduction Cell Migration Regulation Of Cell Communication Regulation Of Signaling Regulation Of Organelle Organization Cytoskeleton Regulation Of Multicellular Organismal Process Microtubule Binding Tau Protein Binding Regulation Of Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cytoplasm Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Signal Transduction Cell Motility Negative Regulation Of Catabolic Process Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Plasma Membrane Bounded Cell Projection Negative Regulation Of Protein Metabolic Process Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Cellular Component Organization Modulation Of Chemical Synaptic Transmission Leukocyte Migration Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Cellular Response To L-glutamate Inclusion Body Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Tubulin Complex Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?