RAB8B and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 12221131)
51

Data Source:
HPRD (two hybrid)

		RAB8B	RAB3IP
Description		RAB8B, member RAS oncogene family	RAB3A interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Endosome Membrane Membrane Trans-Golgi Network Transport Vesicle Phagocytic Vesicle Membrane Cytoplasmic Vesicle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Presynapse	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Lamellipodium Vesicle Ciliary Basal Body Cell Projection Perinuclear Region Of Cytoplasm Proximal Dendrite
	Molecular Function	Nucleotide Binding GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Hydrolase Activity GDP Binding TPR Domain Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding GTPase Binding
	Biological Process	Exocytosis Protein Transport Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Endocytic Recycling Protein Import Into Peroxisome Membrane Positive Regulation Of Corticotropin Secretion Cilium Assembly Cell-substrate Junction Organization	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Protein Transport Negative Regulation Of Filopodium Assembly Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs		Phosphoaminophosphonic acid guanylate ester Guanosine-5'-Diphosphate
Diseases
GWAS		Refractive error ( 32231278) Serum metabolite levels ( 23093944) Social communication problems ( 24564958)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		7 interacting genes: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM	32 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		51762	117177
HPRD ID		11476	10565
Ensembl ID		ENSG00000166128	ENSG00000127328
Uniprot IDs		Q92930	Q96QF0
PDB IDs			4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?		Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Extracellular Exosome Cellular Localization Nuclear Envelope Lumen GTPase Activating Protein Binding Structural Constituent Of Cytoskeleton Negative Regulation Of Cell Projection Organization Regulation Of Cellular Component Organization Regulation Of Filopodium Assembly Amyloid-beta Complex Growth Cone Lamellipodium Synaptic Membrane Plasma Membrane Bounded Cell Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glial Cell Development GTP Binding Regulation Of Receptor Internalization Cell Body Acetylcholine Receptor Activator Activity Lipoprotein Particle Cell Projection Organization Positive Regulation Of Protein Import Edg-2 Lysophosphatidic Acid Receptor Binding Dense Core Granule Membrane Negative Regulation Of Type 2 Mitophagy Ciliary Basal Body-plasma Membrane Docking PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Neuron Projection Development Regulation Of Receptor-mediated Endocytosis Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Vesicle-mediated Transport Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Neuron Projection Development Post-Golgi Vesicle-mediated Transport Localization Within Membrane Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Response To External Biotic Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling	Myosin V Binding Protein Transport Synaptic Vesicle Regulation Of Neuronal Synaptic Plasticity Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Exocytosis Plasma Membrane To Endosome Transport Intracellular Protein Localization Vesicle Organization GTPase Activity Vesicle-mediated Transport Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Endocytic Recycling Trans-Golgi Network Transport Vesicle Endosome Establishment Of Protein Localization Phagocytic Vesicle GTP Binding Vesicle-mediated Transport In Synapse GTP-dependent Protein Binding Secretion By Cell Cytoplasmic Vesicle Recycling Endosome Membrane Extracellular Exosome Regulation Of Long-term Neuronal Synaptic Plasticity Trans-Golgi Network Membrane Organelle Organization Glycerol-3-phosphate Dehydrogenase (quinone) Activity Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Endosomal Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Synaptic Vesicle Endosomal Processing Coated Vesicle Membrane Organelle Fusion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?