RAB8B and RAB3IP

Number of citations of the paper that reports this interaction (PMID 12221131)
45

Data Source:
HPRD (two hybrid)

		RAB8B	RAB3IP
Gene Name		RAB8B, member RAS oncogene family	RAB3A interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Trans-Golgi Network Transport Vesicle Secretory Granule Membrane Phagocytic Vesicle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Extracellular Vesicular Exosome	Nucleus Centrosome Cytosol Cytoskeleton Lamellipodium Ciliary Basal Body
	Molecular Function	GTPase Activity Receptor Binding Protein Binding GTP Binding GDP Binding TPR Domain Binding	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Adherens Junction Organization Cilium Assembly Protein Import Into Peroxisome Membrane Golgi Vesicle Fusion To Target Membrane Positive Regulation Of Corticotropin Secretion Protein Localization To Plasma Membrane	Protein Targeting To Membrane Golgi To Plasma Membrane Transport Organelle Organization Positive Regulation Of Rab GTPase Activity Protein Localization To Organelle Cilium Assembly
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM	19 interactors: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A ZNF410
Entrez ID		51762	117177
HPRD ID		11476	10565
Ensembl ID		ENSG00000166128	ENSG00000127328
Uniprot IDs		F5GY21 Q92930	Q96QF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Localization Organelle Organization Lens Fiber Cell Differentiation Cellular Component Assembly Establishment Of Localization In Cell Exocytosis Cell Cycle Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cytoskeleton Organization Platelet Degranulation Cell Division Execution Phase Of Apoptosis Synapse Assembly Cell Cycle Secretion By Cell Lens Development In Camera-type Eye Protein Polymerization Vesicle-mediated Transport Regulation Of Body Fluid Levels G2/M Transition Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Secretion Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Process Regulation Of Neurogenesis Collateral Sprouting In Absence Of Injury Mitotic Cell Cycle Microtubule-based Process Synapse Organization Membrane Raft Localization Negative Regulation Of Neuron Differentiation Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Indole-3-methanol Regulation Of Cell Development Membrane Organization Epithelial Cell Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Activation Of Anaphase-promoting Complex Activity Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Apoptotic Process Central Nervous System Development Bergmann Glial Cell Differentiation Salivary Gland Cavitation Programmed Cell Death Mitotic Cell Cycle Phase Transition Protein Complex Assembly Cell Cycle Phase Transition	Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Fusion To Target Membrane Protein Secretion Protein Localization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Ras Protein Signal Transduction Organelle Fusion Protein Transport Establishment Of Protein Localization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Regulated Secretory Pathway Membrane Fusion Organelle Localization Vesicle-mediated Transport Regulation Of Regulated Secretory Pathway Secretion By Cell Vesicle Organization Keratinization Skin Development Regulation Of Cellular Localization Vesicle Fusion Synaptic Transmission Organelle Organization Regulation Of Neuronal Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Small GTPase Mediated Signal Transduction Epidermis Development Secretion Positive Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Secretion N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Positive Regulation Of Transport Cellular Protein Localization Keratinocyte Differentiation Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane
Tagcloud ?		1a 1b adaptor addiction ap2 ca1 cation channels cyclic electrophysiology gated hcn hcn1 hcn2 hippocampal hyperpolarization imbalance learning ltp maze morphine mu2 neurological pka potentiation sc tpr trip8b vital	11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Difference) ?		1a 1b adaptor addiction ap2 ca1 cation channels cyclic electrophysiology gated hcn hcn1 hcn2 hippocampal hyperpolarization imbalance learning ltp maze morphine mu2 neurological pka potentiation sc tpr trip8b vital	11q23 12q11 12q14 12q15 12q21 17q11 17q12 3p12 6p21 6q21 6q23 9p13 9p21 acc accs adenoid amplicons ccnd3 cnas cnot2 glipr1l1 mec mecs mucoepidermoid numa1 pax5 pvrl1 sdc statuses
Tagcloud (Intersection) ?