XPO6 and DIAPH1

Number of citations of the paper that reports this interaction (PMID 14592989)
52

Data Source:
HPRD (in vitro)

		XPO6	DIAPH1
Gene Name		exportin 6	diaphanous-related formin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane	Cytoplasm Ruffle Membrane Neuron Projection Mitotic Spindle
	Molecular Function	Protein Binding Ran GTPase Binding Protein Transporter Activity	Actin Binding Receptor Binding Protein Binding Profilin Binding Rho GTPase Binding Identical Protein Binding Ion Channel Binding Poly(A) RNA Binding
	Biological Process	Protein Export From Nucleus	Cytoskeleton Organization Sensory Perception Of Sound Regulation Of Cell Shape Actin Filament Polymerization Positive Regulation Of Cell Migration Neuron Projection Development Regulation Of Microtubule-based Process Protein Localization To Microtubule Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Histamine
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ACTB DIAPH1 NUP62 PFN1 VASP	15 interactors: APBB1 BAIAP2 CDC7 CENPA GAS7 NEDD4 PAX6 PKD2 PRPF40A RAC1 RHOA RHOC TCERG1 WBP4 XPO6
Entrez ID		23214	1729
HPRD ID		10525	03670
Ensembl ID		ENSG00000169180	ENSG00000131504
Uniprot IDs		B3KW08 D3DWF9 Q96QU8	O60610 Q6URC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Actin Filament-based Process Neural Tube Closure Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Neural Tube Formation Embryonic Epithelial Tube Formation Epithelial Tube Formation Neuron Projection Development Nervous System Development Tube Formation Positive Regulation Of Protein Complex Assembly Morphogenesis Of Embryonic Epithelium Regulation Of Actin Filament Polymerization Neuron Development Platelet Activation Neural Tube Development Developmental Process Cell Junction Assembly Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Positive Regulation Of Ruffle Assembly Immune Response-activating Cell Surface Receptor Signaling Pathway Protein Localization To Microtubule Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Cellular Response To Stimulus Regulation Of Cellular Component Size Positive Regulation Of Cell Migration Cellular Response To Histamine Regulation Of Protein Complex Assembly Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Histamine Epithelial Tube Morphogenesis Generation Of Neurons Axon Guidance Negative Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process	Regulation Of Cell Morphogenesis Neuron Projection Development Cell Cycle Regulation Of Cellular Component Organization Neuron Development Neuron Projection Morphogenesis Cell Cycle Process Neuron Differentiation Cytoskeleton Organization Cell Projection Organization Cell Projection Morphogenesis Skeletal Muscle Satellite Cell Migration Cell Part Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Generation Of Neurons Cell Morphogenesis Positive Regulation Of DNA Metabolic Process Nervous System Development Regulation Of Cell Shape Neurogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Anatomical Structure Morphogenesis Cell Development Locomotion Cell Migration Cell Motility Regulation Of Cell Cycle Chemotaxis Organelle Organization Mitotic Cell Cycle Process Response To External Stimulus Response To Stress Mitotic Cell Cycle Protein Localization Cell Cycle Arrest Positive Regulation Of Intracellular Signal Transduction Cellular Protein Localization Cell Division Regulation Of Cell Development Microtubule Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Cell Projection Organization Regulation Of Cell Cycle Process Negative Regulation Of Neuron Differentiation Wound Healing, Spreading Of Cells
Tagcloud ?			5q 5q31 aberrantly abnormality autonomous cd14 del deregulated formin granulocytes hematologic heterozygosity heterozygous hypersensitive innate knockout lenalidomide lineages lipopolysaccharide mdia1 mdss mechanistically messenger mimicking neoplasm polymerization rescued toll underscore
Tagcloud (Difference) ?			5q 5q31 aberrantly abnormality autonomous cd14 del deregulated formin granulocytes hematologic heterozygosity heterozygous hypersensitive innate knockout lenalidomide lineages lipopolysaccharide mdia1 mdss mechanistically messenger mimicking neoplasm polymerization rescued toll underscore
Tagcloud (Intersection) ?