UFD1L and IGHM

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		UFD1L	IGHM
Gene Name		ubiquitin fusion degradation 1 like (yeast)	immunoglobulin heavy constant mu
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Extracellular Space Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome Pentameric IgM Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Blood Microparticle
	Molecular Function	Ubiquitin-specific Protease Activity Receptor Binding Protein Binding Protein Complex Binding	Single-stranded DNA Binding Antigen Binding Phosphatidylcholine Binding Immunoglobulin Receptor Binding Peptidoglycan Binding
	Biological Process	Skeletal System Development Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Adaptive Immune Response Antibacterial Humoral Response Innate Immune Response Defense Response To Gram-negative Bacterium
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: A2M AMFR ANAPC2 F13A1 GZMK IGHM MASP1 NEDD8 NGFR NPLOC4 NUB1 PIK3CA PPHLN1 SNX1 TAF1C TIAM2 TP53 UBXN6 VCP	19 interactors: APP CD22 CD79A CEP72 GADD45A GSK3B HPR HSPA5 IGJ MAPKAPK3 PTK2 SH3GL2 SMN1 TK1 UBQLN4 UFD1L VPREB1 VPREB3 ZAK
Entrez ID		7353	3507
HPRD ID		06778	00912
Ensembl ID		ENSG00000070010
Uniprot IDs		Q541A5 Q92890
PDB IDs		2YUJ
Enriched GO Terms of Interacting Partners?		Proteolysis Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Complement Activation ER-nucleus Signaling Pathway Response To Growth Factor Regulation Of Fibroblast Apoptotic Process Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Response To Endoplasmic Reticulum Stress Blood Coagulation Hemostasis Regulation Of Complement Activation Cellular Response To Organic Substance Response To Organic Substance Platelet Activation Regulation Of Proteasomal Protein Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Neurotrophin TRK Receptor Signaling Pathway Vesicle-mediated Transport Neurotrophin Signaling Pathway Regulation Of Humoral Immune Response Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Regulation Of Body Fluid Levels Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process	Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Response To External Stimulus Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation ER Overload Response Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Endocytosis Axon Guidance Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of Neuron Differentiation Regulation Of Signal Transduction Vesicle-mediated Transport Platelet Activation Immune System Process Axonogenesis Central Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Growth Factor Stimulus Cell Death Death Chemotaxis Response To Growth Factor Regulation Of Catalytic Activity Regulation Of Protein Folding In Endoplasmic Reticulum Fetal Process Involved In Parturition Regulation Of MAPK Cascade Neuron Projection Morphogenesis System Development Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Neurogenesis
Tagcloud ?			aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam2 icam3 ighg3 il7r lck lesional separating sfn v2
Tagcloud (Difference) ?			aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam2 icam3 ighg3 il7r lck lesional separating sfn v2
Tagcloud (Intersection) ?