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UFD1L and TIAM2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
UFD1L
TIAM2
Gene Name
ubiquitin fusion degradation 1 like (yeast)
T-cell lymphoma invasion and metastasis 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Cytosol
Membrane
Lamellipodium
Filopodium
Growth Cone
Extracellular Vesicular Exosome
Molecular Function
Ubiquitin-specific Protease Activity
Receptor Binding
Protein Binding
Protein Complex Binding
Receptor Signaling Protein Activity
Guanyl-nucleotide Exchange Factor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Biological Process
Skeletal System Development
Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Small GTPase Mediated Signal Transduction
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Apoptotic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Apoptotic Signaling Pathway
Pathways
Rho GTPase cycle
PPARA activates gene expression
Signaling by GPCR
GPCR downstream signaling
Signalling by NGF
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Cell death signalling via NRAGE, NRIF and NADE
Signaling by Rho GTPases
NRAGE signals death through JNK
G alpha (12/13) signalling events
p75 NTR receptor-mediated signalling
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
19 interactors:
A2M
AMFR
ANAPC2
F13A1
GZMK
IGHM
MASP1
NEDD8
NGFR
NPLOC4
NUB1
PIK3CA
PPHLN1
SNX1
TAF1C
TIAM2
TP53
UBXN6
VCP
9 interactors:
ANXA7
DISC1
DNM2
H2AFX
PARD3
SH3GL2
TK1
TNIK
UFD1L
Entrez ID
7353
26230
HPRD ID
06778
05273
Ensembl ID
ENSG00000070010
ENSG00000146426
Uniprot IDs
Q541A5
Q92890
B3KW11
E9PKT1
Q8IVF5
PDB IDs
2YUJ
Enriched GO Terms of Interacting Partners
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Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
ER-associated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Complement Activation
ER-nucleus Signaling Pathway
Response To Growth Factor
Regulation Of Fibroblast Apoptotic Process
Protein Modification By Small Protein Conjugation
Regulation Of Proteolysis
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Response To Endoplasmic Reticulum Stress
Blood Coagulation
Hemostasis
Regulation Of Complement Activation
Cellular Response To Organic Substance
Response To Organic Substance
Platelet Activation
Regulation Of Proteasomal Protein Catabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Vesicle-mediated Transport
Neurotrophin Signaling Pathway
Regulation Of Humoral Immune Response
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Positive Regulation Of Protein K63-linked Deubiquitination
Regulation Of Body Fluid Levels
Protein Ubiquitination
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Wound Healing
Positive Regulation Of Cell Death
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Membrane Organization
Anatomical Structure Development
Developmental Process
Generation Of Neurons
System Development
Neurogenesis
Multicellular Organismal Development
Regulation Of Neuron Projection Development
Regulation Of Cellular Component Organization
Fetal Process Involved In Parturition
Organelle Localization
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Post-Golgi Vesicle-mediated Transport
Cell Differentiation
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Cell Projection Organization
Regulation Of Cell Morphogenesis
Regulation Of Cell Projection Organization
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Nervous System Development
Synaptic Vesicle Transport
Negative Regulation Of Membrane Tubulation
Skeletal Muscle Cell Proliferation
Regulation Of Neuron Differentiation
Cellular Localization
Response To Stimulus
Neuron Projection Morphogenesis
Regulation Of Neurogenesis
Cell Proliferation
Response To Cortisol
Apical Constriction
Thymidine Metabolic Process
Asymmetric Cell Division
Establishment Of Vesicle Localization
Vesicle Localization
Deoxyribonucleoside Monophosphate Biosynthetic Process
Neuron Projection Development
Cell Projection Morphogenesis
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Cell Development
Cell Part Morphogenesis
Activation Of JNKK Activity
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
Cellular Component Assembly
Protein Localization
Positive Regulation Of Myelination
Golgi Vesicle Transport
Neuron Development
Wnt Signaling Pathway
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Tagcloud (Intersection)
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