IGHM and CEP72

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IGHM	CEP72
Gene Name		immunoglobulin heavy constant mu	centrosomal protein 72kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome Pentameric IgM Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Blood Microparticle	Centrosome Cytosol
	Molecular Function	Single-stranded DNA Binding Antigen Binding Phosphatidylcholine Binding Immunoglobulin Receptor Binding Peptidoglycan Binding	Protein Binding Identical Protein Binding
	Biological Process	Adaptive Immune Response Antibacterial Humoral Response Innate Immune Response Defense Response To Gram-negative Bacterium	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spindle Organization Gamma-tubulin Complex Localization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Ulcerative colitis ( 20228799)
Protein-Protein Interactions		19 interactors: APP CD22 CD79A CEP72 GADD45A GSK3B HPR HSPA5 IGJ MAPKAPK3 PTK2 SH3GL2 SMN1 TK1 UBQLN4 UFD1L VPREB1 VPREB3 ZAK	17 interactors: ATXN7 CATIP FAM90A1 IGHM KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417
Entrez ID		3507	55722
HPRD ID		00912	07685
Ensembl ID			ENSG00000112877
Uniprot IDs			Q9P209
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Response To External Stimulus Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation ER Overload Response Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Endocytosis Axon Guidance Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of Neuron Differentiation Regulation Of Signal Transduction Vesicle-mediated Transport Platelet Activation Immune System Process Axonogenesis Central Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Growth Factor Stimulus Cell Death Death Chemotaxis Response To Growth Factor Regulation Of Catalytic Activity Regulation Of Protein Folding In Endoplasmic Reticulum Fetal Process Involved In Parturition Regulation Of MAPK Cascade Neuron Projection Morphogenesis System Development Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Neurogenesis	Intraciliary Transport Cilium Organization Cellular Nitrogen Compound Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam2 icam3 ighg3 il7r lck lesional separating sfn v2
Tagcloud (Difference) ?		aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam2 icam3 ighg3 il7r lck lesional separating sfn v2
Tagcloud (Intersection) ?