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UFD1L and F13A1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
UFD1L
F13A1
Gene Name
ubiquitin fusion degradation 1 like (yeast)
coagulation factor XIII, A1 polypeptide
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Extracellular Region
Platelet Alpha Granule Lumen
Blood Microparticle
Molecular Function
Ubiquitin-specific Protease Activity
Receptor Binding
Protein Binding
Protein Complex Binding
Protein-glutamine Gamma-glutamyltransferase Activity
Metal Ion Binding
Biological Process
Skeletal System Development
Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Platelet Degranulation
Blood Coagulation
Peptide Cross-linking
Platelet Activation
Pathways
Common Pathway
Response to elevated platelet cytosolic Ca2+
Platelet degranulation
Platelet activation, signaling and aggregation
Formation of Fibrin Clot (Clotting Cascade)
Drugs
1,2-Propanediol
N-Acetyl-Serine
Diseases
GWAS
End-stage coagulation (
23381943
)
MRI atrophy measures (
21116278
)
Protein-Protein Interactions
19 interactors:
A2M
AMFR
ANAPC2
F13A1
GZMK
IGHM
MASP1
NEDD8
NGFR
NPLOC4
NUB1
PIK3CA
PPHLN1
SNX1
TAF1C
TIAM2
TP53
UBXN6
VCP
13 interactors:
ANXA7
CDKN1A
F13B
F2
FGA
FGG
FN1
NUDT21
PTK2
SERPINF2
SH3GL2
TK1
UFD1L
Entrez ID
7353
2162
HPRD ID
06778
00604
Ensembl ID
ENSG00000070010
ENSG00000124491
Uniprot IDs
Q541A5
Q92890
P00488
PDB IDs
2YUJ
1EVU
1EX0
1F13
1FIE
1GGT
1GGU
1GGY
1QRK
Enriched GO Terms of Interacting Partners
?
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
ER-associated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Complement Activation
ER-nucleus Signaling Pathway
Response To Growth Factor
Regulation Of Fibroblast Apoptotic Process
Protein Modification By Small Protein Conjugation
Regulation Of Proteolysis
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Response To Endoplasmic Reticulum Stress
Blood Coagulation
Hemostasis
Regulation Of Complement Activation
Cellular Response To Organic Substance
Response To Organic Substance
Platelet Activation
Regulation Of Proteasomal Protein Catabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Vesicle-mediated Transport
Neurotrophin Signaling Pathway
Regulation Of Humoral Immune Response
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Positive Regulation Of Protein K63-linked Deubiquitination
Regulation Of Body Fluid Levels
Protein Ubiquitination
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Wound Healing
Positive Regulation Of Cell Death
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Hemostasis
Regulation Of Body Fluid Levels
Platelet Activation
Blood Coagulation
Wound Healing
Response To Wounding
Platelet Degranulation
Regulation Of Cell Morphogenesis
Regulation Of Cellular Component Organization
Cell Activation
Extracellular Matrix Organization
Extracellular Structure Organization
Acute-phase Response
Regulation Of Cell Shape
Positive Regulation Of Phosphorylation
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Negative Regulation Of Wound Healing
Protein Complex Assembly
Acute Inflammatory Response
Negative Regulation Of Fibrinolysis
Response To Stress
Positive Regulation Of Heterotypic Cell-cell Adhesion
Regulation Of Blood Coagulation
Regulation Of Fibrinolysis
Response To Metal Ion
Exocytosis
Response To Calcium Ion
Regulation Of Phosphorylation
Regulation Of Cell-cell Adhesion
Defense Response
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Wound Healing
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cell Development
Vesicle-mediated Transport
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Endothelial Cell Apoptotic Process
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Collagen Biosynthetic Process
Regulation Of Cell Differentiation
ERBB Signaling Pathway
Positive Regulation Of Collagen Metabolic Process
Response To Inorganic Substance
Cell-matrix Adhesion
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Fibrinolysis
Secretion By Cell
Tagcloud
?
10p13
17q21
5q15
6p24
australian
british
cl
cleft
crtl1
d1s58
d1s65
der
excluded
flank
inheritance
linkage
lip
lod
multipoint
palate
rara
syndromic
theta
unrelated
van
vim
vws
woude
z
Tagcloud (Difference)
?
10p13
17q21
5q15
6p24
australian
british
cl
cleft
crtl1
d1s58
d1s65
der
excluded
flank
inheritance
linkage
lip
lod
multipoint
palate
rara
syndromic
theta
unrelated
van
vim
vws
woude
z
Tagcloud (Intersection)
?