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UFD1L and TAF1C
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
UFD1L
TAF1C
Gene Name
ubiquitin fusion degradation 1 like (yeast)
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Nucleoplasm
Molecular Function
Ubiquitin-specific Protease Activity
Receptor Binding
Protein Binding
Protein Complex Binding
DNA Binding
Protein Binding
Biological Process
Skeletal System Development
Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Chromatin Silencing At RDNA
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Gene Expression
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Pathways
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
SIRT1 negatively regulates rRNA Expression
Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Autism (
22843504
)
Visceral adipose tissue adjusted for BMI (
22589738
)
Protein-Protein Interactions
19 interactors:
A2M
AMFR
ANAPC2
F13A1
GZMK
IGHM
MASP1
NEDD8
NGFR
NPLOC4
NUB1
PIK3CA
PPHLN1
SNX1
TAF1C
TIAM2
TP53
UBXN6
VCP
14 interactors:
H2AFX
POLR1E
RRN3
SMN1
TAF1A
TAF1B
TAF1D
TBP
TK1
TP53
TRIM24
TTR
UBTF
UFD1L
Entrez ID
7353
9013
HPRD ID
06778
05364
Ensembl ID
ENSG00000070010
ENSG00000103168
Uniprot IDs
Q541A5
Q92890
B3KUE8
Q15572
PDB IDs
2YUJ
Enriched GO Terms of Interacting Partners
?
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
ER-associated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Complement Activation
ER-nucleus Signaling Pathway
Response To Growth Factor
Regulation Of Fibroblast Apoptotic Process
Protein Modification By Small Protein Conjugation
Regulation Of Proteolysis
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Response To Endoplasmic Reticulum Stress
Blood Coagulation
Hemostasis
Regulation Of Complement Activation
Cellular Response To Organic Substance
Response To Organic Substance
Platelet Activation
Regulation Of Proteasomal Protein Catabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Vesicle-mediated Transport
Neurotrophin Signaling Pathway
Regulation Of Humoral Immune Response
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Positive Regulation Of Protein K63-linked Deubiquitination
Regulation Of Body Fluid Levels
Protein Ubiquitination
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Wound Healing
Positive Regulation Of Cell Death
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Transcription Initiation From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Elongation
DNA-templated Transcription, Initiation
Chromatin Silencing At RDNA
Regulation Of Gene Expression, Epigenetic
Chromatin Silencing
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Gene Expression
RRNA Transcription
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Gene Silencing
Cellular Nitrogen Compound Metabolic Process
Transcription, DNA-templated
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
RNA Metabolic Process
RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Signal Transduction By P53 Class Mediator
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase I Promoter
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Negative Regulation Of Biosynthetic Process
Protein-DNA Complex Assembly
Transcription From RNA Polymerase III Promoter
Cellular Macromolecular Complex Assembly
Cellular Component Assembly
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Metabolic Process
Fetal Process Involved In Parturition
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromitophagy
Skeletal Muscle Cell Proliferation
Tagcloud
?
analysed
blocking
c8
coding
crc
frameshift
gc
harboured
heterogeneity
instability
intratumoural
ith
microsatellite
mononucleotide
msi
mss
mutational
regional
ribosomal
rrna
somatic
strand
summary
taf1a
taf1b
tata
tbp
tumourigenesis
ubf
Tagcloud (Difference)
?
analysed
blocking
c8
coding
crc
frameshift
gc
harboured
heterogeneity
instability
intratumoural
ith
microsatellite
mononucleotide
msi
mss
mutational
regional
ribosomal
rrna
somatic
strand
summary
taf1a
taf1b
tata
tbp
tumourigenesis
ubf
Tagcloud (Intersection)
?