IGHM and CD22

Number of citations of the paper that reports this interaction (PMID 8475064)
35

Data Source:
HPRD (in vivo)

		IGHM	CD22
Gene Name		immunoglobulin heavy constant mu	CD22 molecule
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome Pentameric IgM Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Blood Microparticle	Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Single-stranded DNA Binding Antigen Binding Phosphatidylcholine Binding Immunoglobulin Receptor Binding Peptidoglycan Binding	Protein Binding Carbohydrate Binding
	Biological Process	Adaptive Immune Response Antibacterial Humoral Response Innate Immune Response Defense Response To Gram-negative Bacterium	Cell Adhesion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APP CD22 CD79A CEP72 GADD45A GSK3B HPR HSPA5 IGJ MAPKAPK3 PTK2 SH3GL2 SMN1 TK1 UBQLN4 UFD1L VPREB1 VPREB3 ZAK	16 interactors: AP2M1 ATP2B4 CD19 GRB2 HP IGHM INPP5D LCP2 LYN PIK3R1 PLCG1 PTPN6 PTPRC SHC1 ST6GAL1 SYK
Entrez ID		3507	933
HPRD ID		00912	00114
Ensembl ID			ENSG00000012124
Uniprot IDs			P20273 Q0EAF5 Q32M46
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Response To External Stimulus Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation ER Overload Response Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Endocytosis Axon Guidance Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of Neuron Differentiation Regulation Of Signal Transduction Vesicle-mediated Transport Platelet Activation Immune System Process Axonogenesis Central Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Growth Factor Stimulus Cell Death Death Chemotaxis Response To Growth Factor Regulation Of Catalytic Activity Regulation Of Protein Folding In Endoplasmic Reticulum Fetal Process Involved In Parturition Regulation Of MAPK Cascade Neuron Projection Morphogenesis System Development Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Neurogenesis	Immune Response-regulating Cell Surface Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune System Process Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Regulation Of Immune Response Wound Healing Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Immune Response Regulation Of Immune System Process Positive Regulation Of Immune Response Defense Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Fc Receptor Signaling Pathway Response To Wounding Innate Immune Response Platelet Activation B Cell Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Stress Positive Regulation Of Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Cell Migration ERBB Signaling Pathway Locomotion Cell Motility Regulation Of Lymphocyte Activation Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Regulation Of B Cell Differentiation Positive Regulation Of Homotypic Cell-cell Adhesion Cell Activation Neurotrophin Signaling Pathway Movement Of Cell Or Subcellular Component T Cell Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Activation Regulation Of Kinase Activity Regulation Of T Cell Activation Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Response To Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway
Tagcloud ?		aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam2 icam3 ighg3 il7r lck lesional separating sfn v2	arthritis arthropathy cd1 cd15 cd3 chemoattractant enlarged focally granulocytes hybridisation immunoblot immunophenotype immunophenotypes infiltrate interdigitating intima kim4 kim8 leucocyte lining lymphocytes multinucleated perivascular preferential psoriatic synovial synovitis traffic vicinity
Tagcloud (Difference) ?		aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam2 icam3 ighg3 il7r lck lesional separating sfn v2	arthritis arthropathy cd1 cd15 cd3 chemoattractant enlarged focally granulocytes hybridisation immunoblot immunophenotype immunophenotypes infiltrate interdigitating intima kim4 kim8 leucocyte lining lymphocytes multinucleated perivascular preferential psoriatic synovial synovitis traffic vicinity
Tagcloud (Intersection) ?