UFD1L and PPHLN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		UFD1L	PPHLN1
Gene Name		ubiquitin fusion degradation 1 like (yeast)	periphilin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	Ubiquitin-specific Protease Activity Receptor Binding Protein Binding Protein Complex Binding	Poly(A) RNA Binding
	Biological Process	Skeletal System Development Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Keratinization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: A2M AMFR ANAPC2 F13A1 GZMK IGHM MASP1 NEDD8 NGFR NPLOC4 NUB1 PIK3CA PPHLN1 SNX1 TAF1C TIAM2 TP53 UBXN6 VCP	20 interactors: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 MTUS2 NAGK PAXIP1 PPL SEPT8 SNCAIP SQSTM1 TGM2 TOMM20 TP53BP2 TSGA10 UFD1L VIM
Entrez ID		7353	51535
HPRD ID		06778	10488
Ensembl ID		ENSG00000070010	ENSG00000134283
Uniprot IDs		Q541A5 Q92890	B7Z8L1 E9PAX8 F8W6A0 Q8NEY8
PDB IDs		2YUJ
Enriched GO Terms of Interacting Partners?		Proteolysis Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Complement Activation ER-nucleus Signaling Pathway Response To Growth Factor Regulation Of Fibroblast Apoptotic Process Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Response To Endoplasmic Reticulum Stress Blood Coagulation Hemostasis Regulation Of Complement Activation Cellular Response To Organic Substance Response To Organic Substance Platelet Activation Regulation Of Proteasomal Protein Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Neurotrophin TRK Receptor Signaling Pathway Vesicle-mediated Transport Neurotrophin Signaling Pathway Regulation Of Humoral Immune Response Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Regulation Of Body Fluid Levels Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process	Response To Ionizing Radiation Apoptotic Process Programmed Cell Death Cell Death Death Response To Radiation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Cell Cycle Positive Regulation Of Histone Acetylation Signal Transduction By P53 Class Mediator Developmental Process Regulation Of Histone H3-K4 Methylation Response To Abiotic Stimulus Positive Regulation Of Peptidyl-lysine Acetylation Apoptotic Signaling Pathway Organ Development Positive Regulation Of Protein Acetylation Astrocyte Development Multicellular Organismal Development Anatomical Structure Development System Development Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cell Cycle Positive Regulation Of Histone Methylation Intrinsic Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Astrocyte Differentiation Regulation Of Histone Acetylation Central Nervous System Development Positive Regulation Of Gene Expression Regulation Of Histone Methylation Neuron Apoptotic Process Positive Regulation Of Histone H4-K20 Methylation Cell Dedifferentiation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Apoptotic Process In Bone Marrow Regulation Of Signaling Neuron Death Positive Regulation Of Histone Modification Execution Phase Of Apoptosis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation N-acetylmannosamine Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Differentiation Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage
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