Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TXK and NELFCD
Number of citations of the paper that reports this interaction (PMID
14684750
)
3
Data Source:
HPRD
(in vitro)
TXK
NELFCD
Gene Name
TXK tyrosine kinase
negative elongation factor complex member C/D
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Nucleoplasm
Membrane
NELF Complex
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Regulatory Region DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Non-membrane Spanning Protein Tyrosine Kinase Activity
Receptor Binding
Protein Binding
ATP Binding
Protein Binding
Biological Process
Cytokine Production
NK T Cell Differentiation
Adaptive Immune Response
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Activation Of Phospholipase C Activity
T Cell Differentiation
Interferon-gamma Production
Interleukin-4 Production
Positive Regulation Of Interferon-gamma Production
Peptidyl-tyrosine Autophosphorylation
Regulation Of Cell Proliferation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Autophosphorylation
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Positive Regulation Of Interferon-gamma-mediated Signaling Pathway
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Gene Expression
Viral Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Transcription
Pathways
Fc epsilon receptor (FCERI) signaling
FCERI mediated Ca+2 mobilization
Innate Immune System
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Crohn's disease (
23128233
)
Protein-Protein Interactions
10 interactors:
CCR5
CTLA4
ERBB2
ERBB3
FYN
LCP2
NELFCD
SH2D2A
SRC
YTHDC1
19 interactors:
AAMP
AR
ARAF
ARPC4
CACNA1A
DNAJA1
ENDOV
EPRS
FRMD5
GSTM4
HDAC11
MTA1
NELFA
PRMT5
SERF2
SMAD4
TXK
UBE3A
ZNF638
Entrez ID
7294
51497
HPRD ID
02505
16096
Ensembl ID
ENSG00000074966
ENSG00000101158
Uniprot IDs
P42681
H0UI80
Q8IXH7
PDB IDs
2DM0
Enriched GO Terms of Interacting Partners
?
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Immune Response
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Immune Response
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Negative Regulation Of Cell Adhesion
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Wound Healing
Regulation Of Cell Adhesion
Cell Surface Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
T Cell Costimulation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of T Cell Activation
Regulation Of Immune System Process
Immune System Process
Response To Wounding
Defense Response
Cellular Response To Platelet-derived Growth Factor Stimulus
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Innate Immune Response
Response To Platelet-derived Growth Factor
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Lymphocyte Activation
Phosphatidylinositol-mediated Signaling
Antigen Receptor-mediated Signaling Pathway
Regulation Of Cell Activation
Phosphatidylinositol 3-kinase Signaling
Viral Process
Platelet Activation
Cellular Response To Growth Factor Stimulus
Protein Autophosphorylation
Response To Growth Factor
Chemotaxis
Positive Regulation Of T Cell Activation
Positive Regulation Of Signal Transduction
Negative Regulation Of T Cell Differentiation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Immune Response
Leukocyte Migration
Androgen Receptor Signaling Pathway
Endothelial Cell Activation
Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Growth
Regulation Of Protein Ubiquitination
Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Death
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Integrin Biosynthetic Process
Cerebellar Molecular Layer Development
Sperm Entry
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stimulus
Cellular Metabolic Process
Prostate Gland Development
Heterocycle Metabolic Process
Biosynthetic Process
Prolyl-tRNA Aminoacylation
Vestibular Nucleus Development
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Nephrogenic Mesenchyme Morphogenesis
Positive Regulation Of Protein Autoubiquitination
Regulation Of Establishment Of Protein Localization
Rhythmic Process
Circadian Regulation Of Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Glutamyl-tRNA Aminoacylation
Positive Regulation Of Integrin Biosynthetic Process
Cerebellum Maturation
Nephrogenic Mesenchyme Development
Metanephric Mesenchyme Morphogenesis
Musculoskeletal Movement, Spinal Reflex Action
Regulation Of Protein Autoubiquitination
NK T Cell Differentiation
Positive Regulation Of Cellular Metabolic Process
Cellular Component Assembly
Tagcloud
?
abl
abundant
acting
bcr
bmx
brdg1
btk
constitute
docking
downstream
effectors
feature
feedback
homology
integrins
itk
lyn
participate
ph
pleckstrin
proline
ptks
pyk2
ramos
sh2
syk
tec
termed
triggered
Tagcloud (Difference)
?
abl
abundant
acting
bcr
bmx
brdg1
btk
constitute
docking
downstream
effectors
feature
feedback
homology
integrins
itk
lyn
participate
ph
pleckstrin
proline
ptks
pyk2
ramos
sh2
syk
tec
termed
triggered
Tagcloud (Intersection)
?