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NELFCD and CACNA1A
Number of citations of the paper that reports this interaction (PMID
21078624
)
14
Data Source:
BioGRID
(two hybrid)
NELFCD
CACNA1A
Gene Name
negative elongation factor complex member C/D
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Membrane
NELF Complex
Nucleus
Cytoplasm
Plasma Membrane
Voltage-gated Calcium Channel Complex
Integral Component Of Membrane
Dendrite
Cell Projection
Neuronal Cell Body
Molecular Function
Protein Binding
Voltage-gated Calcium Channel Activity
Protein Binding
High Voltage-gated Calcium Channel Activity
Syntaxin Binding
Metal Ion Binding
Biological Process
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Gene Expression
Viral Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Transcription
Sulfur Amino Acid Metabolic Process
Glucose Metabolic Process
Energy Reserve Metabolic Process
Positive Regulation Of Cytosolic Calcium Ion Concentration
Gamma-aminobutyric Acid Signaling Pathway
Synaptic Transmission
Neuromuscular Synaptic Transmission
Synapse Assembly
Adult Walking Behavior
Cell Death
Gamma-aminobutyric Acid Secretion
Regulation Of Acetylcholine Secretion, Neurotransmission
Cell Growth
Calcium Ion-dependent Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Transmission Of Nerve Impulse
Spinal Cord Motor Neuron Differentiation
Cerebellum Maturation
Cerebellar Molecular Layer Development
Cerebellar Purkinje Cell Differentiation
Vestibular Nucleus Development
Cellular Chloride Ion Homeostasis
Negative Regulation Of Hormone Biosynthetic Process
Regulation Of Ion Transmembrane Transport
Synaptic Transmission, Glutamatergic
Neurotransmitter Metabolic Process
Hormone Metabolic Process
Receptor Clustering
Negative Regulation Of Neuron Apoptotic Process
Small Molecule Metabolic Process
Behavioral Response To Pain
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Dendrite Morphogenesis
Regulation Of Axonogenesis
Regulation Of Insulin Secretion
Musculoskeletal Movement, Spinal Reflex Action
Neuromuscular Process Controlling Balance
Membrane Depolarization
Rhythmic Synaptic Transmission
Calcium Ion Import
Calcium Ion Transmembrane Transport
Membrane Depolarization During Action Potential
Pathways
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Integration of energy metabolism
Regulation of insulin secretion
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
Transmission across Chemical Synapses
Drugs
Pregabalin
Verapamil
Loperamide
Bepridil
Diseases
GWAS
Protein-Protein Interactions
19 interactors:
AAMP
AR
ARAF
ARPC4
CACNA1A
DNAJA1
ENDOV
EPRS
FRMD5
GSTM4
HDAC11
MTA1
NELFA
PRMT5
SERF2
SMAD4
TXK
UBE3A
ZNF638
92 interactors:
ABCA2
ABI1
ACTN1
AGRN
ALDOA
AMIGO2
AP2M1
ARHGAP22
ASNA1
BTG3
BZRAP1
C1QTNF1
CABP1
CACNB1
CACNB4
CALM2
CALM3
CKAP5
CRIM1
CRMP1
CSNK2B
CYSRT1
DNAJB5
EFEMP1
EFEMP2
EHMT2
EIF3A
FBLN1
GNB1
GOLGA6L5P
GRN
HECW1
HHATL
HIVEP1
HSPG2
IP6K1
JAG2
KALRN
KHDRBS3
KIAA1191
LAMB1
LLGL1
LPHN1
LRP1
LTBP1
LTBP3
LTBP4
MANBAL
MATK
MATN2
MEGF6
MEGF8
MIA3
MOAP1
NDUFB8
NELFCD
NELL1
NELL2
NOTCH1
NOXA1
OLIG1
PCSK5
PCSK6
PMM1
PPIG
PPM1A
PPP1R12C
PTGDS
PUF60
RBM12B
RIMBP2
RPL31
RPS17
SCP2
SPRY1
SRRM4
SRSF1
SUMF2
SYT1
TAF15
TELO2
TSC22D1
TSPAN7
TUBB2B
UQCRC2
VARS
VPS52
VWF
WBP1
YLPM1
ZCCHC17
ZNF233
Entrez ID
51497
773
HPRD ID
16096
03004
Ensembl ID
ENSG00000101158
ENSG00000141837
Uniprot IDs
H0UI80
Q8IXH7
B5TYJ1
O00555
Q9NS89
PDB IDs
3BXK
Enriched GO Terms of Interacting Partners
?
Androgen Receptor Signaling Pathway
Endothelial Cell Activation
Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Growth
Regulation Of Protein Ubiquitination
Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Death
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Integrin Biosynthetic Process
Cerebellar Molecular Layer Development
Sperm Entry
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stimulus
Cellular Metabolic Process
Prostate Gland Development
Heterocycle Metabolic Process
Biosynthetic Process
Prolyl-tRNA Aminoacylation
Vestibular Nucleus Development
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Nephrogenic Mesenchyme Morphogenesis
Positive Regulation Of Protein Autoubiquitination
Regulation Of Establishment Of Protein Localization
Rhythmic Process
Circadian Regulation Of Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Glutamyl-tRNA Aminoacylation
Positive Regulation Of Integrin Biosynthetic Process
Cerebellum Maturation
Nephrogenic Mesenchyme Development
Metanephric Mesenchyme Morphogenesis
Musculoskeletal Movement, Spinal Reflex Action
Regulation Of Protein Autoubiquitination
NK T Cell Differentiation
Positive Regulation Of Cellular Metabolic Process
Cellular Component Assembly
Secretion By Cell
Secretion
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Voltage-gated Calcium Channel Activity
Detection Of Visible Light
Enzyme Linked Receptor Protein Signaling Pathway
Detection Of Light Stimulus
Multicellular Organismal Development
Phototransduction, Visible Light
Anatomical Structure Development
Cellular Localization
Axon Development
Developmental Process
Establishment Of Localization In Cell
Phototransduction
Regulation Of Cellular Process
System Development
Axonogenesis
Regulation Of Calcium Ion Transmembrane Transport
Regulation Of Calcium Ion Transmembrane Transporter Activity
Detection Of Abiotic Stimulus
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Platelet Degranulation
Cell Morphogenesis Involved In Neuron Differentiation
Anatomical Structure Morphogenesis
Regulation Of Cation Channel Activity
Axon Guidance
Nervous System Development
Detection Of Calcium Ion
Regulation Of Intracellular Cholesterol Transport
Regulation Of Cell Communication By Electrical Coupling
Neuron Projection Morphogenesis
Exocytosis
Neuron Projection Development
Cellular Response To Growth Factor Stimulus
Neuron Differentiation
Inositol Phosphate Metabolic Process
Cell Projection Morphogenesis
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Cell Morphogenesis Involved In Differentiation
Cell Part Morphogenesis
Response To Growth Factor
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cation Channel Activity
Platelet Activation
Cell-cell Signaling
Nerve Growth Factor Processing
Pathogenesis
Neurotrophin TRK Receptor Signaling Pathway
Tagcloud
?
acetazolamide
ataxia
attacks
autosomal
causative
causing
coincidence
confutes
defect
dysarthria
dystonia
ea
ea2
encodes
episodes
episodic
gait
gated
heterogeneous
inherited
migraine
mim
nonsense
oculomotor
paroxysmal
q
varied
voltage
Tagcloud (Difference)
?
acetazolamide
ataxia
attacks
autosomal
causative
causing
coincidence
confutes
defect
dysarthria
dystonia
ea
ea2
encodes
episodes
episodic
gait
gated
heterogeneous
inherited
migraine
mim
nonsense
oculomotor
paroxysmal
q
varied
voltage
Tagcloud (Intersection)
?