NELFCD and ZNF638

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NELFCD	ZNF638
Gene Name		negative elongation factor complex member C/D	zinc finger protein 638
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Membrane NELF Complex	Nucleoplasm Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Nucleotide Binding Double-stranded DNA Binding RNA Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Splicing
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Height ( 23456168)
Protein-Protein Interactions		19 interactors: AAMP AR ARAF ARPC4 CACNA1A DNAJA1 ENDOV EPRS FRMD5 GSTM4 HDAC11 MTA1 NELFA PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638	13 interactors: CALCOCO2 CCDC85B EFEMP2 FHL2 HOOK2 KIAA1279 KRT15 KRT19 KRTAP4-12 NELFCD PLSCR1 SPP1 WWP1
Entrez ID		51497	27332
HPRD ID		16096	11736
Ensembl ID		ENSG00000101158	ENSG00000075292
Uniprot IDs		H0UI80 Q8IXH7	A8K583 Q14966
PDB IDs
Enriched GO Terms of Interacting Partners?		Androgen Receptor Signaling Pathway Endothelial Cell Activation Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Growth Regulation Of Protein Ubiquitination Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Negative Regulation Of Integrin Biosynthetic Process Cerebellar Molecular Layer Development Sperm Entry Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Regulation Of Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Stimulus Cellular Metabolic Process Prostate Gland Development Heterocycle Metabolic Process Biosynthetic Process Prolyl-tRNA Aminoacylation Vestibular Nucleus Development Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Nephrogenic Mesenchyme Morphogenesis Positive Regulation Of Protein Autoubiquitination Regulation Of Establishment Of Protein Localization Rhythmic Process Circadian Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Glutamyl-tRNA Aminoacylation Positive Regulation Of Integrin Biosynthetic Process Cerebellum Maturation Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Musculoskeletal Movement, Spinal Reflex Action Regulation Of Protein Autoubiquitination NK T Cell Differentiation Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly	Viral Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Atrial Cardiac Muscle Cell Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Osteoblast Differentiation Negative Regulation Of Cell Growth Regulation Of Viral Process Striated Muscle Cell Development Phosphatidylserine Biosynthetic Process Negative Regulation Of Gene Expression Muscle Cell Development Negative Regulation Of Collateral Sprouting Negative Regulation Of Biosynthetic Process Negative Regulation Of Axon Regeneration Placenta Development Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Response To Organic Substance Phospholipid Scrambling Striated Muscle Cell Differentiation
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