TRAF6 and USP15

  • Number of citations of the paper that reports this interaction (PMID 20622874)
  • 46
  • Data Source:
  • BioGRID (enzymatic study)

TRAF6

USP15

Gene Name TNF receptor-associated factor 6, E3 ubiquitin protein ligase ubiquitin specific peptidase 15
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulmonary function decline ( 22424883)
Protein-Protein Interactions 144 interactors: ABL1 APP ATM ATP6V1E1 ATXN3 BECN1 BMPR1B CALCOCO2 CASP8 CAV1 CBL CD40 CYLD ECSIT EDA2R EDARADD FHL2 FYN GTF2I HIF1A HSPA4 IKBKG IL17RB IRAK1 IRAK2 IRAK3 IRAK4 IRF5 IRF7 IRF8 JAK2 KCNQ1 MALT1 MAP2K1 MAP2K6 MAP2K7 MAP3K11 MAP3K14 MAP3K3 MAP3K5 MAP3K7 MAP3K8 MAPK14 MAPK8 MAPT MAST2 MAVS MBP MCL1 MEOX2 MTOR NGFR NGFRAP1 NTRK1 NTRK2 NUMBL OTUB1 OTUB2 OTUD7B PELI3 PINK1 PLEKHF2 PLEKHO1 POLI PPP4C PRKCZ PSMB5 PSMC1 PSMC2 PSMC3 PSMD1 PSMD12 PSMD13 PSMD6 PSMD7 PTPN6 RIPK2 RNF114 SIGIRR SPHK1 SPOP SQSTM1 SRC STAMBP STRADB STUB1 SYK TAB1 TAB2 TAB3 TAX1BP1 TDP2 TGFBR1 TICAM1 TICAM2 TIFA TIRAP TLR3 TMEM189-UBE2V1 TNFAIP3 TNFRSF11A TNFRSF13B TNFRSF19 TNFSF11 TRAF1 TRAF2 TRAF3IP1 TRAF3IP2 TRAF4 TRAF5 TRAF7 TRAFD1 TRAM1 TRIM17 TRIM25 TRIM37 UBB UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2L3 UBE2N UBE2V1 UBOX5 UEVLD USP1 USP15 USP2 USP21 USP39 USP4 USP5 USP7 VPS52 XIAP YBX1 YES1 ZFAND5 ZMYND11 ZNF675 ZRANB1 45 interactors: BAP1 BMPR1A BRAP CARD9 CCDC57 FHL1 HIST2H2BE JOSD1 MAD1L1 OTUB1 PHF7 PLA2G2A RBCK1 RNF126 RNF144B SART3 SENP3 SENP8 SMAD3 SPDL1 STAM STK33 TRAF6 TRIM17 TRIM21 TRIM25 TRIM46 TRIM5 TRIM54 TRIM63 TRIM74 UBC UBE2S UCHL1 UCHL3 USP14 USP20 USP21 USP28 USP33 USP4 USP51 USP7 USP8 YOD1
Entrez ID 7189 9958
HPRD ID 03833 05293
Ensembl ID ENSG00000135655
Uniprot IDs Q9Y4K3 Q9Y4E8
PDB IDs 1LB4 1LB5 1LB6 2ECI 2JMD 3HCS 3HCT 3HCU 1W6V 3LMN 3PPA 3PV1 3T9L 4A3O 4A3P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf3  traf5  transduction 
antitumor  bacterial  boost  challenge  characterized  class  crucial  deficiency  degradation  deubiquitinases  dub  dubs  e3  enhanced  induce  ligase  mdm2  negatively  nfatc2  physiological  promoted  regulated  regulator  responses  stabilized  targeting  targets  turn  ubiquitin 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf3  traf5  transduction 
antitumor  bacterial  boost  challenge  characterized  class  crucial  deficiency  degradation  deubiquitinases  dub  dubs  e3  enhanced  induce  ligase  mdm2  negatively  nfatc2  physiological  promoted  regulated  regulator  responses  stabilized  targeting  targets  turn  ubiquitin 
Tagcloud (Intersection) ?