USP15 and SENP8

  • Number of citations of the paper that reports this interaction (PMID 22626734)
  • 2
  • Data Source:
  • BioGRID (enzymatic study)

USP15

SENP8

Gene Name ubiquitin specific peptidase 15 SUMO/sentrin specific peptidase family member 8
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulmonary function decline ( 22424883)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions 45 interactors: BAP1 BMPR1A BRAP CARD9 CCDC57 FHL1 HIST2H2BE JOSD1 MAD1L1 OTUB1 PHF7 PLA2G2A RBCK1 RNF126 RNF144B SART3 SENP3 SENP8 SMAD3 SPDL1 STAM STK33 TRAF6 TRIM17 TRIM21 TRIM25 TRIM46 TRIM5 TRIM54 TRIM63 TRIM74 UBC UBE2S UCHL1 UCHL3 USP14 USP20 USP21 USP28 USP33 USP4 USP51 USP7 USP8 YOD1 12 interactors: COPS2 CUL1 CUL2 CUL4A GPS1 NEDD8 PLA2G2A SMURF1 UBB USP15 USP21 USP28
Entrez ID 9958 123228
HPRD ID 05293 09784
Ensembl ID ENSG00000135655 ENSG00000166192
Uniprot IDs Q9Y4E8 A8K8D3 Q96LD8
PDB IDs 1W6V 3LMN 3PPA 3PV1 3T9L 4A3O 4A3P 1XT9 2BKQ 2BKR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
antitumor  bacterial  boost  challenge  characterized  class  crucial  deficiency  degradation  deubiquitinases  dub  dubs  e3  enhanced  induce  ligase  mdm2  negatively  nfatc2  physiological  promoted  regulated  regulator  responses  stabilized  targeting  targets  turn  ubiquitin 
attributed  bca3  bind  conversely  crucial  cullins  deacetylase  du145  link  mcf7  modification  nad  necrosis  nedd8  neddylated  neddylation  nfkappab  p65  prolongs  protease  recruit  reversed  silencing  sirt1  span  substrates  ubiquitin  worms  yeast 
Tagcloud (Difference) ?
antitumor  bacterial  boost  challenge  characterized  class  deficiency  degradation  deubiquitinases  dub  dubs  e3  enhanced  induce  ligase  mdm2  negatively  nfatc2  physiological  promoted  regulated  regulator  responses  stabilized  targeting  targets  turn 
attributed  bca3  bind  conversely  cullins  deacetylase  du145  link  mcf7  modification  nad  necrosis  nedd8  neddylated  neddylation  nfkappab  p65  prolongs  protease  recruit  reversed  silencing  sirt1  span  substrates  worms  yeast 
Tagcloud (Intersection) ?
crucial  ubiquitin