TRAF6 and MAP2K6

  • Number of citations of the paper that reports this interaction (PMID 16313339)
  • 43
  • Data Source:
  • HPRD (in vitro)

TRAF6

MAP2K6

Gene Name TNF receptor-associated factor 6, E3 ubiquitin protein ligase mitogen-activated protein kinase kinase 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
Protein-Protein Interactions 144 interactors: ABL1 APP ATM ATP6V1E1 ATXN3 BECN1 BMPR1B CALCOCO2 CASP8 CAV1 CBL CD40 CYLD ECSIT EDA2R EDARADD FHL2 FYN GTF2I HIF1A HSPA4 IKBKG IL17RB IRAK1 IRAK2 IRAK3 IRAK4 IRF5 IRF7 IRF8 JAK2 KCNQ1 MALT1 MAP2K1 MAP2K6 MAP2K7 MAP3K11 MAP3K14 MAP3K3 MAP3K5 MAP3K7 MAP3K8 MAPK14 MAPK8 MAPT MAST2 MAVS MBP MCL1 MEOX2 MTOR NGFR NGFRAP1 NTRK1 NTRK2 NUMBL OTUB1 OTUB2 OTUD7B PELI3 PINK1 PLEKHF2 PLEKHO1 POLI PPP4C PRKCZ PSMB5 PSMC1 PSMC2 PSMC3 PSMD1 PSMD12 PSMD13 PSMD6 PSMD7 PTPN6 RIPK2 RNF114 SIGIRR SPHK1 SPOP SQSTM1 SRC STAMBP STRADB STUB1 SYK TAB1 TAB2 TAB3 TAX1BP1 TDP2 TGFBR1 TICAM1 TICAM2 TIFA TIRAP TLR3 TMEM189-UBE2V1 TNFAIP3 TNFRSF11A TNFRSF13B TNFRSF19 TNFSF11 TRAF1 TRAF2 TRAF3IP1 TRAF3IP2 TRAF4 TRAF5 TRAF7 TRAFD1 TRAM1 TRIM17 TRIM25 TRIM37 UBB UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2L3 UBE2N UBE2V1 UBOX5 UEVLD USP1 USP15 USP2 USP21 USP39 USP4 USP5 USP7 VPS52 XIAP YBX1 YES1 ZFAND5 ZMYND11 ZNF675 ZRANB1 21 interactors: DCTN1 LRRK2 MAP2K4 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 PKN1 PLCB2 RELA SMAD7 STAT4 TAOK2 TLR3 TRAF6 ZAK
Entrez ID 7189 5608
HPRD ID 03833 03155
Ensembl ID
Uniprot IDs Q9Y4K3 A8K3Y2 P52564
PDB IDs 1LB4 1LB5 1LB6 2ECI 2JMD 3HCS 3HCT 3HCU 2Y8O 3ENM 3FME 3VN9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf3  traf5  transduction 
camk1  centriole  dkk1  enah  endosome  geo  gpsm2  inference  kcnq3  kpna2  lcn2  lef1  lysosome  multivesicular  nkx2  nr5a1  nup62  ontology  phosphoinositide  sfrp4  slc4a3  sort1  sstr5  stx1a  subnetwork  tbl3  transport  tshb  ube2c 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf3  traf5  transduction 
camk1  centriole  dkk1  enah  endosome  geo  gpsm2  inference  kcnq3  kpna2  lcn2  lef1  lysosome  multivesicular  nkx2  nr5a1  nup62  ontology  phosphoinositide  sfrp4  slc4a3  sort1  sstr5  stx1a  subnetwork  tbl3  transport  tshb  ube2c 
Tagcloud (Intersection) ?