TEAD1 and VGLL4

Number of citations of the paper that reports this interaction (PMID 15140898)
17

Data Source:
HPRD (in vitro)

		TEAD1	VGLL4
Gene Name		TEA domain family member 1 (SV40 transcriptional enhancer factor)	vestigial-like family member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus	Nucleus
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Hippo Signaling	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Height ( 20881960)	Anorexia nervosa ( 21079607) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000)
Protein-Protein Interactions		17 interactors: GCAT HLA-DMB INSR MAX MEF2A MEF2BNB-MEF2B MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17	5 interactors: CDK6 MEF2A MEF2C TEAD1 TERF2IP
Entrez ID		7003	9686
HPRD ID		01802	11672
Ensembl ID		ENSG00000187079	ENSG00000144560
Uniprot IDs		A4FUP2 P28347 Q59EF3	G5E9M7 Q14135
PDB IDs		2HZD 3KYS
Enriched GO Terms of Interacting Partners?		Heart Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Developmental Growth Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Heart Tube Development Platelet Formation Positive Regulation Of Growth Platelet Morphogenesis Biosynthetic Process Cardiac Myofibril Assembly Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A RNA Metabolic Process Heart Development Transcription From RNA Polymerase II Promoter Regulation Of Developmental Growth Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Gene Expression Striated Muscle Tissue Development Regulation Of RNA Metabolic Process Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Chamber Development Positive Regulation Of Cell Proliferation In Bone Marrow Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Positive Regulation Of Organ Growth Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Tissue Development Ventricular Cardiac Myofibril Assembly Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Development Embryonic Organ Development	Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Positive Regulation Of Cell Proliferation In Bone Marrow Embryonic Heart Tube Morphogenesis Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Embryonic Heart Tube Development Ventricular Cardiac Myofibril Assembly Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of Epithelial Cell Proliferation Regulation Of Osteoblast Differentiation Cardiac Ventricle Formation Cardiac Chamber Formation Germinal Center Formation Positive Regulation Of Alkaline Phosphatase Activity Regulation Of Macrophage Apoptotic Process Regulation Of Germinal Center Formation Glomerulus Morphogenesis Cellular Response To Fluid Shear Stress Secondary Heart Field Specification Mitochondrion Distribution Embryonic Viscerocranium Morphogenesis Regulation Of Sarcomere Organization Muscle Cell Fate Commitment Regulation Of Myeloid Cell Differentiation Monocyte Differentiation Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Megakaryocyte Differentiation Regulation Of Protein Homodimerization Activity Cartilage Morphogenesis Positive Regulation Of Cardiac Muscle Cell Differentiation Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Ventricular Cardiac Muscle Cell Development Cellular Response To Antibiotic Heart Formation Regulation Of Ossification Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Platelet Formation Mesenchyme Development Platelet Morphogenesis Cardiac Myofibril Assembly Specification Of Organ Identity Cellular Response To Toxic Substance Heart Morphogenesis
Tagcloud ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?