TEAD1 and HLA-DMB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TEAD1	HLA-DMB
Gene Name		TEA domain family member 1 (SV40 transcriptional enhancer factor)	major histocompatibility complex, class II, DM beta
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus	Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	MHC Class II Protein Complex Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Hippo Signaling	MHC Class II Protein Complex Assembly Peptide Antigen Assembly With MHC Class II Protein Complex Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		17 interactors: GCAT HLA-DMB INSR MAX MEF2A MEF2BNB-MEF2B MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17	10 interactors: CD63 CD74 CD82 CUL3 DPM2 HLA-DMA HLA-DOB HLA-DRA MDM2 TEAD1
Entrez ID		7003	3109
HPRD ID		01802	00831
Ensembl ID		ENSG00000187079	ENSG00000242574
Uniprot IDs		A4FUP2 P28347 Q59EF3	P28068
PDB IDs		2HZD 3KYS	1HDM 2BC4 4FQX 4GBX 4I0P
Enriched GO Terms of Interacting Partners?		Heart Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Developmental Growth Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Heart Tube Development Platelet Formation Positive Regulation Of Growth Platelet Morphogenesis Biosynthetic Process Cardiac Myofibril Assembly Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A RNA Metabolic Process Heart Development Transcription From RNA Polymerase II Promoter Regulation Of Developmental Growth Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Gene Expression Striated Muscle Tissue Development Regulation Of RNA Metabolic Process Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Chamber Development Positive Regulation Of Cell Proliferation In Bone Marrow Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Positive Regulation Of Organ Growth Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Tissue Development Ventricular Cardiac Myofibril Assembly Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Development Embryonic Organ Development	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Antigen Processing And Presentation Positive Thymic T Cell Selection Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Complex Assembly Thymic T Cell Selection Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Chaperone Mediated Protein Folding Requiring Cofactor Positive T Cell Selection Immune Response Regulation Of Immune System Process Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion T Cell Selection Regulation Of Signal Transduction By P53 Class Mediator Regulation Of T Cell Activation Positive Regulation Of Cell Activation Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Immune Response 'de Novo' Posttranslational Protein Folding Positive Regulation Of Cell Cycle Phase Transition 'de Novo' Protein Folding Chaperone-mediated Protein Folding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process T Cell Differentiation In Thymus Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Cellular Component Assembly Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Lymphocyte Activation Macrophage Migration Inhibitory Factor Signaling Pathway Cellular Response To UV-C Cellular Response To Vitamin B1 Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Immune System Process Regulation Of Cell Activation Polysaccharide Assembly With MHC Class II Protein Complex Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Mitotic Cell Cycle Regulation Of T Cell Differentiation Regulation Of Response To DNA Damage Stimulus
Tagcloud ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?