TEAD1 and VGLL2

Number of citations of the paper that reports this interaction (PMID 12376544)
26

Data Source:
HPRD (in vivo, in vitro)

		TEAD1	VGLL2
Gene Name		TEA domain family member 1 (SV40 transcriptional enhancer factor)	vestigial-like family member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus	Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Transcription Coactivator Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Hippo Signaling	Transcription, DNA-templated Skeletal Muscle Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Height ( 20881960)	Height ( 20881960)
Protein-Protein Interactions		17 interactors: GCAT HLA-DMB INSR MAX MEF2A MEF2BNB-MEF2B MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17	3 interactors: MEF2C TEAD1 TEAD3
Entrez ID		7003	245806
HPRD ID		01802	18282
Ensembl ID		ENSG00000187079	ENSG00000170162
Uniprot IDs		A4FUP2 P28347 Q59EF3	Q8N8G2
PDB IDs		2HZD 3KYS
Enriched GO Terms of Interacting Partners?		Heart Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Developmental Growth Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Heart Tube Development Platelet Formation Positive Regulation Of Growth Platelet Morphogenesis Biosynthetic Process Cardiac Myofibril Assembly Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A RNA Metabolic Process Heart Development Transcription From RNA Polymerase II Promoter Regulation Of Developmental Growth Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Gene Expression Striated Muscle Tissue Development Regulation Of RNA Metabolic Process Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Chamber Development Positive Regulation Of Cell Proliferation In Bone Marrow Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Positive Regulation Of Organ Growth Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Tissue Development Ventricular Cardiac Myofibril Assembly Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Development Embryonic Organ Development	Positive Regulation Of Stem Cell Maintenance Regulation Of Stem Cell Maintenance Hippo Signaling Positive Regulation Of Cell Development Positive Regulation Of Stem Cell Differentiation Embryonic Heart Tube Morphogenesis Embryonic Heart Tube Development Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Mesenchyme Development Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A Heart Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Nephron Tubule Epithelial Cell Differentiation Positive Regulation Of Cell Proliferation In Bone Marrow Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Embryonic Organ Morphogenesis Positive Regulation Of Behavioral Fear Response Positive Regulation Of Macrophage Apoptotic Process Epithelial Tube Morphogenesis Positive Regulation Of Protein Homodimerization Activity Cellular Response To Parathyroid Hormone Stimulus Transcription, DNA-templated Tube Morphogenesis Positive Regulation Of Myeloid Cell Apoptotic Process Ventricular Cardiac Myofibril Assembly RNA Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Differentiation Cardiac Ventricle Formation Embryonic Organ Development Positive Regulation Of Cellular Metabolic Process Cardiac Chamber Formation Morphogenesis Of An Epithelium Heart Development Germinal Center Formation Lateral Mesoderm Development
Tagcloud ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?		520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?