VGLL4

Description		vestigial like family member 4
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GO Annotations	Cellular Component	Nucleus
	Molecular Function	Transcription Coactivator Binding Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Negative Regulation Of Hippo Signaling Positive Regulation Of Protein Catabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Cardiac Muscle Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa ( 21079607) Appendicular lean mass ( 33097823) Blond vs. brown/black hair color ( 30531825) Body mass index ( 28892062) Chronic obstructive pulmonary disease ( 30804561) Clopidogrel active metabolite levels ( 28207573) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 28196072) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Moderate-to-late spontaneous preterm birth ( 31194736) Offspring birth weight ( 31043758) Optic disc area ( 28073927) Relative hand skill in reading disability ( 24068947) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		10 interacting genes: CDK6 DAPK1 LRRK1 LRRK2 MEF2A MEF2C MFHAS1 TEAD1 TEAD2 TERF2IP
Entrez ID		9686
HPRD ID		11672
Ensembl ID		ENSG00000144560
Uniprot IDs		A0A0A6YYI5 G5E9M9 Q14135
PDB IDs		8YTF
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Signal Transduction TEAD-YAP Complex Protein Serine Kinase Activity GTP Binding Syntaxin-1 Binding Mitochondrion Distribution Protein Serine/threonine Kinase Activity Positive Regulation Of Metabolic Process Hippo Signaling Cellular Response To Metal Ion Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Kinase Activity Cellular Developmental Process MAPK Cascade Transcription Regulator Complex Positive Regulation Of Macromolecule Metabolic Process Cyclin D2-CDK6 Complex DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death DNA-binding Transcription Factor Activity Mitochondrion Localization Excitatory Postsynaptic Potential Sinoatrial Valve Morphogenesis Regulation Of Macrophage Activation Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Regulation Of Stem Cell Differentiation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cellular Response To Stress Cell Differentiation Cyclin D3-CDK6 Complex Regulation Of Gene Expression Cyclin D1-CDK6 Complex FBXO Family Protein Binding Cellular Response To Oxygen-containing Compound ERK5 Cascade Response To Metal Ion Animal Organ Development Cellular Response To Calcium Ion Muscle Cell Fate Determination Regulation Of Neurotransmitter Secretion Regulation Of Synaptic Transmission, Glutamatergic Nephron Tubule Epithelial Cell Differentiation Cellular Response To Trichostatin A Embryonic Heart Tube Morphogenesis
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