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HLA-DMB and HLA-DMA
Number of citations of the paper that reports this interaction (PMID
8139690
)
46
Data Source:
HPRD
(in vivo)
HLA-DMB
HLA-DMA
Gene Name
major histocompatibility complex, class II, DM beta
major histocompatibility complex, class II, DM alpha
Image
Gene Ontology Annotations
Cellular Component
Lysosomal Membrane
Integral Component Of Membrane
Late Endosome Membrane
MHC Class II Protein Complex
Lysosomal Membrane
Multivesicular Body
Cell Surface
Membrane
Integral Component Of Membrane
Late Endosome Membrane
MHC Class II Protein Complex
Extracellular Vesicular Exosome
Molecular Function
MHC Class II Protein Complex Binding
MHC Class II Protein Complex Binding
Biological Process
MHC Class II Protein Complex Assembly
Peptide Antigen Assembly With MHC Class II Protein Complex
Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of T Cell Proliferation
Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Peptide Antigen Assembly With MHC Class II Protein Complex
Protein Transport
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Thymic T Cell Selection
Positive Regulation Of T Cell Differentiation
Inner Ear Development
Positive Regulation Of Immune Response
Chaperone Mediated Protein Folding Requiring Cofactor
Pathways
MHC class II antigen presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
CD63
CD74
CD82
CUL3
DPM2
HLA-DMA
HLA-DOB
HLA-DRA
MDM2
TEAD1
8 interactors:
B3GAT1
CD74
CD82
HLA-DMB
HLA-DOA
HLA-DRA
HLA-DRB1
U2AF2
Entrez ID
3109
3108
HPRD ID
00831
00830
Ensembl ID
ENSG00000242574
ENSG00000204257
Uniprot IDs
P28068
Q31604
Q5SP00
Q6ICR9
PDB IDs
1HDM
2BC4
4FQX
4GBX
4I0P
4I0P
Enriched GO Terms of Interacting Partners
?
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen
Peptide Antigen Assembly With MHC Class II Protein Complex
MHC Class II Protein Complex Assembly
Antigen Processing And Presentation
Positive Thymic T Cell Selection
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Protein Complex Assembly
Thymic T Cell Selection
Negative Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Chaperone Mediated Protein Folding Requiring Cofactor
Positive T Cell Selection
Immune Response
Regulation Of Immune System Process
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
T Cell Selection
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Immune Response
'de Novo' Posttranslational Protein Folding
Positive Regulation Of Cell Cycle Phase Transition
'de Novo' Protein Folding
Chaperone-mediated Protein Folding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
T Cell Differentiation In Thymus
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Cellular Component Assembly
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Lymphocyte Activation
Macrophage Migration Inhibitory Factor Signaling Pathway
Cellular Response To UV-C
Cellular Response To Vitamin B1
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Lymphocyte Differentiation
Immune System Process
Regulation Of Cell Activation
Polysaccharide Assembly With MHC Class II Protein Complex
Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Positive Regulation Of Mitotic Cell Cycle
Regulation Of T Cell Differentiation
Regulation Of Response To DNA Damage Stimulus
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Peptide Antigen Assembly With MHC Class II Protein Complex
MHC Class II Protein Complex Assembly
Antigen Processing And Presentation Of Peptide Antigen
Antigen Processing And Presentation
Regulation Of T Cell Activation
Regulation Of Cell-cell Adhesion
Regulation Of Lymphocyte Activation
Regulation Of Cell Activation
Polysaccharide Assembly With MHC Class II Protein Complex
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Activation
Positive Regulation Of Cell Adhesion
Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immune Response
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Cellular Protein Complex Assembly
Protein Complex Assembly
Immune System Process
Negative Regulation Of Immune System Process
T Cell Costimulation
Cytokine-mediated Signaling Pathway
Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Macrophage Migration Inhibitory Factor Signaling Pathway
Negative Regulation Of T Cell Activation
Negative Regulation Of Leukocyte Cell-cell Adhesion
T Cell Receptor Signaling Pathway
Negative Regulation Of Homotypic Cell-cell Adhesion
Cellular Response To Cytokine Stimulus
Positive Regulation Of Lymphocyte Proliferation
Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of Mononuclear Cell Proliferation
Regulation Of T Cell Differentiation
Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Receptor-mediated Signaling Pathway
Cellular Macromolecular Complex Assembly
Negative Regulation Of Lymphocyte Activation
Negative Regulation Of Cell-cell Adhesion
Cellular Response To Interferon-gamma
Regulation Of T Cell Proliferation
Response To Cytokine
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Negative Regulation Of Leukocyte Activation
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