ELOA2 and NKAPD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ELOA2	NKAPD1
Description		elongin A2	NKAP domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Elongin Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: CALCOCO2 CBX5 CDK6 CEP70 CHD2 COIL DVL2 ELOB ELOC HSF2BP KRTAP4-12 KXD1 NKAPD1 RNPS1 SOHLH2 SREK1IP1 TRAF2 TRIM37 ZBTB43 ZCCHC10 ZNF138 ZNF165 ZNF23	50 interacting genes: AAMP ACTN1 ACTN2 ACTN3 AGPAT3 AP1M1 AP2M1 ARL6IP4 BEND7 C1orf35 CCDC106 CCNL1 CDCA8 CEP70 COIL CT45A1 DRC4 ELOA2 EXOSC5 FAM133A FRMD6 GOLGA8K H2BC15 HMGXB4 KRCC1 MACROH2A1 MAPK8 MCRS1 MKRN3 MYO15B NKAPL NXF1 PRPF3 PRPF40A RBM39 RNF151 RP9 RPS25 S100B SDCBP SDCBP2 SNRNP25 SREK1IP1 STAC3 TAF1A THAP1 TXLNA U2AF2 ZNF317 ZNF41
Entrez ID		51224	55216
HPRD ID		18169	07695
Ensembl ID		ENSG00000206181	ENSG00000150776
Uniprot IDs		Q8IYF1	Q6ZUT1
PDB IDs
Enriched GO Terms of Interacting Partners?		Target-directed MiRNA Degradation Elongin Complex Protein-macromolecule Adaptor Activity Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Negative Regulation Of MiRNA-mediated Gene Silencing MiRNA Catabolic Process Cul5-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Hematopoietic Stem Cell Differentiation Ubiquitin Ligase Complex MiRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Tumor Necrosis Factor Receptor Binding Aggresome Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cyclin D2-CDK6 Complex TORC2 Complex Disassembly RNA Polymerase III General Transcription Initiation Factor Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Initiation At RNA Polymerase II Promoter Transcription Corepressor Binding RNA Catabolic Process Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding	Pseudopodium RNA Splicing Nuclear Speck Focal Adhesion Assembly Microtubule Cytoskeleton Nucleus RNA Processing Muscle Cell Development Cell-substrate Junction Assembly Cell-substrate Junction Organization MRNA Processing Nucleoplasm MRNA Metabolic Process Identical Protein Binding Nucleic Acid Metabolic Process Sarcomere Cortical Actin Cytoskeleton Clathrin Adaptor Complex RNA Metabolic Process Transmembrane Transporter Binding
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