LMNB2 and CA8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LMNB2	CA8
Description		lamin B2	carbonic anhydrase 8
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Lamina Intermediate Filament Nuclear Membrane	Cytoplasm
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Nuclear Envelope Organization Cytoskeleton Organization Nuclear Migration Heterochromatin Formation Nuclear Pore Localization Protein Localization To Nuclear Envelope	Positive Regulation Of Calcium-mediated Signaling
Pathways
Drugs			Zonisamide
Diseases
GWAS			Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) High myopia ( 33830181) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 29483656 28991256 30285260 25056061) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		28 interacting genes: AMOT AMOTL2 CA8 CCDC120 CCDC88B CDC37 EFHC2 FH GOLGA2 LZTS1 MFAP1 MID2 OVOL1 PIBF1 POU6F2 PPP1R13B PRKCD SVIL TFIP11 THAP1 TMPO TP53BP2 TRIM27 TSGA10IP USP2 WASHC3 ZC2HC1C ZFHX3	14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3
Entrez ID		84823	767
HPRD ID		01037	00266
Ensembl ID		ENSG00000176619	ENSG00000178538
Uniprot IDs		Q03252	P35219
PDB IDs		2LLL	2W2J
Enriched GO Terms of Interacting Partners?		Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Regulation Of Actin Filament Organization Cytoplasm Regulation Of Autophagy Regulation Of Actin Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament-based Process Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription
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