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LMNB2 and PRKCD
Number of citations of the paper that reports this interaction (PMID
1939065
)
5
Data Source:
HPRD
(in vitro)
LMNB2
PRKCD
Gene Name
lamin B2
protein kinase C, delta
Image
Gene Ontology Annotations
Cellular Component
Nuclear Inner Membrane
Lamin Filament
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Cell-cell Junction
Nuclear Matrix
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Molecular_function
Structural Molecule Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Calcium-independent Protein Kinase C Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Enzyme Activator Activity
Enzyme Binding
Insulin Receptor Substrate Binding
Metal Ion Binding
Biological Process
Biological_process
Protein Phosphorylation
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Cycle
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Blood Coagulation
Fibroblast Growth Factor Receptor Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Gene Expression
Regulation Of Receptor Activity
Immunoglobulin Mediated Immune Response
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Cytokine-mediated Signaling Pathway
Termination Of Signal Transduction
Platelet Activation
Negative Regulation Of Actin Filament Polymerization
Negative Regulation Of Protein Binding
Interleukin-10 Production
Interleukin-12 Production
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Glial Cell Apoptotic Process
Positive Regulation Of Protein Dephosphorylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
B Cell Proliferation
Neutrophil Activation
Defense Response To Bacterium
Negative Regulation Of MAP Kinase Activity
Innate Immune Response
Negative Regulation Of Insulin Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Inflammatory Response
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Protein Stabilization
Negative Regulation Of Filopodium Assembly
Interferon-gamma-mediated Signaling Pathway
Negative Regulation Of Platelet Aggregation
Cellular Senescence
Positive Regulation Of Phospholipid Scramblase Activity
Positive Regulation Of Ceramide Biosynthetic Process
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Positive Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Ca-dependent events
Signaling by GPCR
CaM pathway
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
Effects of PIP2 hydrolysis
Interferon gamma signaling
DAP12 signaling
Gastrin-CREB signalling pathway via PKC and MAPK
G alpha (z) signalling events
Role of phospholipids in phagocytosis
Fcgamma receptor (FCGR) dependent phagocytosis
Signaling by PDGF
Calmodulin induced events
Regulation of mRNA stability by proteins that bind AU-rich elements
Apoptotic cleavage of cellular proteins
DAP12 interactions
Opioid Signalling
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
G alpha (q) signalling events
Signaling by EGFR
GPCR downstream signaling
Signaling by VEGF
Calmodulin induced events
Downstream signal transduction
Signaling by EGFR in Cancer
Platelet activation, signaling and aggregation
G alpha (q) signalling events
HuR stabilizes mRNA
DAG and IP3 signaling
VEGFA-VEGFR2 Pathway
CaM pathway
VEGFR2 mediated cell proliferation
Downstream signaling of activated FGFR
Programmed Cell Death
Innate Immune System
Signalling by NGF
PLC beta mediated events
Interferon Signaling
Apoptotic execution phase
Cytokine Signaling in Immune system
Signaling by Ligand-Responsive EGFR Variants in Cancer
G-protein mediated events
NGF signalling via TRKA from the plasma membrane
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
PLC-gamma1 signalling
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Ulcerative colitis (
23128233
)
Ventricular conduction (
21076409
)
Protein-Protein Interactions
3 interactors:
PRKCD
SVIL
TMPO
118 interactors:
ACTA1
ACTA2
ACTB
ADAM9
ADCY7
ADD1
ADD2
ADRA2A
ADRB2
ADRBK1
AFAP1
AKT3
APP
ART3
BDKRB2
C1QBP
CD34
CDCP1
CHAT
CNP
CREBBP
CYTH1
DAB2
DYNC1H1
EEF1A1
EGFR
EIF2S1
ELAVL1
EP300
ESRRA
FLI1
FSCN1
FYN
GABRA1
GAP43
GNA12
GNA13
GNAZ
GNB2L1
GRM5
GSK3A
HABP4
HDAC5
HIST1H1A
HIST1H1B
HNRNPK
HSP90AA1
HSPA4
IGF1R
IKBKB
IL6ST
INSR
IRS1
ITGA6
ITGB2
ITGB4
ITGB7
ITPR1
KCNJ1
KCNJ4
KLF5
LCK
LMNB1
LMNB2
LYN
MACF1
MAPK1
MAPK3
MAPT
MBP
MEP1B
MS4A2
MUC1
NCF1
NCF4
NFE2L2
NUMB
OPRD1
PAK1
PDP1
PDP2
PDPK1
PEBP1
PIK3CA
PIK3CB
PLCB1
PLD2
PLSCR1
PLSCR3
PPARA
PPM1A
PPP1CA
PPP2CA
PPP2R5C
PRKCZ
PRKDC
PTK2B
PTPN22
PTPN6
PTPRA
RAC1
RAF1
RASGRP3
RIPK4
RUNX2
SDC4
SHC1
SRC
STAT1
STAT3
TAGLN
TIAM1
TNFRSF1A
VCP
VHL
YWHAB
YWHAG
YWHAZ
Entrez ID
84823
5580
HPRD ID
01037
01501
Ensembl ID
ENSG00000176619
ENSG00000163932
Uniprot IDs
J9JID7
Q03252
Q05655
PDB IDs
2LLL
1YRK
2YUU
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Phospholipid Scramblase Activity
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Positive Regulation Of Phospholipid Catabolic Process
Interleukin-10 Production
Negative Regulation Of Filopodium Assembly
Interleukin-12 Production
Positive Regulation Of Ceramide Biosynthetic Process
Regulation Of Ceramide Biosynthetic Process
Positive Regulation Of Phospholipid Transport
Negative Regulation Of Platelet Aggregation
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Superoxide Anion Generation
Regulation Of Platelet Aggregation
Negative Regulation Of Platelet Activation
Positive Regulation Of Protein Dephosphorylation
Neutrophil Activation
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Positive Regulation Of Lipid Catabolic Process
Regulation Of Platelet Activation
Cellular Senescence
Negative Regulation Of Insulin Receptor Signaling Pathway
Positive Regulation Of Cytokinesis
B Cell Proliferation
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Filopodium Assembly
Peptidyl-threonine Phosphorylation
Positive Regulation Of Dephosphorylation
Activation Of Phospholipase C Activity
Negative Regulation Of Blood Coagulation
Negative Regulation Of Protein Binding
Positive Regulation Of Phospholipase C Activity
Positive Regulation Of Transporter Activity
Regulation Of Lipid Catabolic Process
Regulation Of Cytokinesis
Negative Regulation Of Coagulation
Positive Regulation Of Lipid Transport
Positive Regulation Of Lipid Biosynthetic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Wound Healing
Positive Regulation Of Response To DNA Damage Stimulus
Termination Of Signal Transduction
Cell Aging
Negative Regulation Of Actin Filament Polymerization
Execution Phase Of Apoptosis
Positive Regulation Of Phospholipase Activity
Regulation Of Cellular Response To Insulin Stimulus
Negative Regulation Of MAP Kinase Activity
Signaling
Cell Communication
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Response To Organic Substance
Positive Regulation Of Metabolic Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Peptide
Cellular Response To Stimulus
Cellular Response To Peptide Hormone Stimulus
Defense Response
Response To Stress
Cellular Response To Organonitrogen Compound
Response To Stimulus
Platelet Activation
Cellular Response To Hormone Stimulus
Regulation Of Signal Transduction
Immune System Process
Positive Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Response To Peptide
Response To Hormone
Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Regulation Of Phosphorus Metabolic Process
Innate Immune Response
Regulation Of Signaling
Response To Peptide Hormone
Response To Wounding
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Response To Growth Factor
Wound Healing
Cell Activation
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Kinase Activity
Hemostasis
Positive Regulation Of Cellular Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Protein Modification Process
Anatomical Structure Development
Positive Regulation Of Protein Phosphorylation
Cellular Response To Insulin Stimulus
Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Fc Receptor Signaling Pathway
Immune Response
Response To Insulin
Tagcloud
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Difference)
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Intersection)
?