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MED22 and MED8
Number of citations of the paper that reports this interaction (PMID
12584197
)
12
Data Source:
HPRD
(in vitro)
MED22
MED8
Gene Name
mediator complex subunit 22
mediator complex subunit 8
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mediator Complex
Nucleoplasm
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Protein Ubiquitination
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
GOLM1
MED11
MED17
MED27
MED30
MED7
MED8
MED9
THOC7
31 interactors:
APP
ARRB2
CCNC
CDK8
CTDP1
HSPB3
KRT40
MED1
MED11
MED12
MED17
MED19
MED20
MED22
MED25
MED26
MED27
MED28
MED30
MED31
MED6
MED7
MED9
PEX14
PHYHIP
PNMA1
SNTA1
TCEB1
THOC7
UBALD1
USP49
Entrez ID
6837
112950
HPRD ID
01713
06991
Ensembl ID
ENSG00000148297
ENSG00000159479
Uniprot IDs
Q15528
Q96G25
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription Initiation From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Stem Cell Maintenance
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Stem Cell Development
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Stem Cell Differentiation
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Cell Differentiation
Androgen Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Cell Differentiation
Intracellular Receptor Signaling Pathway
Viral MRNA Export From Host Cell Nucleus
Cell Development
Cellular Metabolic Process
Intracellular Transport Of Virus
MRNA Export From Nucleus
RNA Export From Nucleus
Cell Differentiation
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Metabolic Process
Biosynthetic Process
Stem Cell Maintenance
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Androgen Receptor Signaling Pathway
Stem Cell Development
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Stem Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Cellular Process
Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Notch Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Binding
Regulation Of Cell Differentiation
Developmental Growth Involved In Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Binding
Cell Development
Negative Regulation Of Fibroblast Proliferation
Axis Elongation
Cellular Response To Transforming Growth Factor Beta Stimulus
Thyroid Hormone Mediated Signaling Pathway
Tagcloud
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Difference)
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Intersection)
?