MED22 and THOC7

Number of citations of the paper that reports this interaction (PMID 12584197)
12

Data Source:
BioGRID (pull down)

		MED22	THOC7
Gene Name		mediator complex subunit 22	THO complex 7 homolog (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mediator Complex	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: GOLM1 MED11 MED17 MED27 MED30 MED7 MED8 MED9 THOC7	10 interactors: ALYREF CHD3 CKAP4 DDX39B GOT2 MED18 MED22 MED8 NIF3L1 THOC5
Entrez ID		6837	80145
HPRD ID		01713	17632
Ensembl ID		ENSG00000148297	ENSG00000163634
Uniprot IDs		Q15528	Q6I9Y2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Stem Cell Maintenance Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Stem Cell Development Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cell Differentiation Androgen Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Cell Differentiation Intracellular Receptor Signaling Pathway Viral MRNA Export From Host Cell Nucleus Cell Development Cellular Metabolic Process Intracellular Transport Of Virus MRNA Export From Nucleus RNA Export From Nucleus Cell Differentiation	Viral MRNA Export From Host Cell Nucleus Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of DNA Damage Checkpoint Regulation Of DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus Nitrogen Compound Metabolic Process RNA Export From Nucleus Regulation Of DNA Damage Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Export MRNA Transport Regulation Of RNA Metabolic Process RNA Transport RNA Localization RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Viral Life Cycle Regulation Of Cell Cycle Checkpoint Nucleocytoplasmic Transport Nuclear Transport Transcription From RNA Polymerase II Promoter RNA Splicing Nucleobase-containing Compound Metabolic Process Biosynthetic Process MRNA Processing Cellular Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process MRNA Metabolic Process RNA Biosynthetic Process Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of Response To DNA Damage Stimulus RNA Processing Fumarate Metabolic Process Dihydrobiopterin Metabolic Process RNA Secondary Structure Unwinding Regulation Of Stem Cell Division
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