BSG and HGS

Number of citations of the paper that reports this interaction (PMID 19019082)
2

Data Source:
BioGRID (pull down)

		BSG	HGS
Gene Name		basigin (Ok blood group)	hepatocyte growth factor-regulated tyrosine kinase substrate
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Sarcolemma Melanosome Membrane Raft Extracellular Vesicular Exosome	Cytoplasm Endosome Early Endosome Cytosol Secretory Granule Early Endosome Membrane Multivesicular Body Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Mannose Binding	Protein Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Pyruvate Metabolic Process Cell Surface Receptor Signaling Pathway Embryo Implantation Blood Coagulation Extracellular Matrix Disassembly Extracellular Matrix Organization Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Cellular Metabolic Process Small Molecule Metabolic Process Response To Mercury Ion Decidualization Leukocyte Migration Response To CAMP Protein Targeting To Plasma Membrane	Protein Targeting To Lysosome Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Endosome To Lysosome Transport Membrane Invagination Positive Regulation Of Gene Expression Endosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Catabolic Process Negative Regulation Of JAK-STAT Cascade Membrane Organization Protein Localization To Membrane Positive Regulation Of Exosomal Secretion
Pathways		Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle Integrin cell surface interactions The citric acid (TCA) cycle and respiratory electron transport Degradation of the extracellular matrix Basigin interactions Cell surface interactions at the vascular wall	Signaling by EGFR EGFR downregulation Endosomal Sorting Complex Required For Transport (ESCRT) Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by EGFRvIII in Cancer
Drugs
Diseases
GWAS			Eye color traits ( 20463881)
Protein-Protein Interactions		10 interactors: CAV1 HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A3 SLC2A4	138 interactors: ABI2 ACLY AHCYL1 APC APLP2 APP ARFIP2 ARL6IP1 ATP1A1 ATP2A2 ATXN1L BCAS2 BEGAIN BRINP3 BSG CASK CBS CCDC103 CCDC114 CCDC33 CEP55 CEP57L1 CLTC CRMP1 CSTF2 CSTF2T CTTNBP2NL DAZAP2 DCTN2 DECR1 DGCR6 DLG4 EGFR EHMT2 EPS15 ESRRG EXOC7 EXOC8 GFAP GFI1B GGA2 GKAP1 HAP1 HNRNPDL HSPA8 IL2RB IL4R ILKAP ING5 INTS4 JAKMIP2 KRT15 KRT18 KRT19 KRT31 KRT38 KRT40 KRT6A LDOC1 LINC00265 LITAF LURAP1 LYST MAGEB4 MAP3K10 MAP3K7 MAPK1IP1L MARK4 MAT2A MED7 MEST MET MIF4GD MKNK1 MRFAP1L1 MTHFD1L NDC80 NEDD4 NEDD4L NF2 NMI NPAS2 NUP54 OSBPL5 P4HA3 PAK1 PEF1 PELP1 PFKM PIK3R1 PITX1 PLD3 POGZ PPP1R16A PPP1R7 PTCD3 RHOBTB3 RPS3A RSU1 SCAMP3 SCRN1 SF3B3 SMAD2 SMAD3 SMAD5 SNAP25 SNX1 SNX5 SNX7 STAM STAM2 STXBP1 SUMO1 SUN2 TADA2A TIMMDC1 TJP2 TMCC2 TOM1L1 TRAK1 TRAP1 TSG101 TUBB TUBB2A UBA1 UBA52 UBB UBC UBE2I UBE4B UBQLN1 UBQLN4 USHBP1 VMP1 VPS37A VPS37C VPS37D ZNF302
Entrez ID		682	9146
HPRD ID		00176	05085
Ensembl ID		ENSG00000172270	ENSG00000185359
Uniprot IDs		P35613 Q54A51	O14964
PDB IDs		3B5H 3I84 3I85 3QQN 3QR2	2D3G 3F1I 3OBQ 3ZYQ 4AVX
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Migration Cell Motility Lactate Transmembrane Transport Plasma Membrane Lactate Transport Lactate Transport Locomotion Movement Of Cell Or Subcellular Component Negative Regulation Of JAK-STAT Cascade Immune System Process Response To Stress Membrane Organization Protein Localization To Membrane Amylopectin Biosynthetic Process Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Uncoating Of Virus Mevalonate Transport Behavioral Response To Nutrient Protein Peptidyl-prolyl Isomerization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Localization Regulation Of JAK-STAT Cascade Nitric Oxide Homeostasis Cellular Response To Oxygen Levels Transport Pyruvate Metabolic Process Monocarboxylic Acid Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Viral Release From Host Cell Viral Process Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Protein Localization To Plasma Membrane Regulation Of Secretion Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Protein Localization To Plasma Membrane Raft Positive Regulation Of Metalloenzyme Activity Caveola Assembly Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway	Establishment Of Localization In Cell Cellular Localization Viral Protein Processing Protein Localization Intracellular Transport Membrane Organization Endosomal Transport Establishment Of Protein Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Transport Regulation Of ERBB Signaling Pathway Virion Assembly Intracellular Transport Of Virus Viral Process Cellular Protein Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Vesicle-mediated Transport Viral Life Cycle Cell Cycle Process Organelle Organization Negative Regulation Of Cellular Response To Growth Factor Stimulus Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cell Cycle Mitotic Cell Cycle Process Transport Post-Golgi Vesicle-mediated Transport Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Metabolic Process Gene Expression Cell Cycle Vesicle Organization Secretion By Cell Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Intracellular Protein Transport Transcription Initiation From RNA Polymerase II Promoter Cellular Process Cellular Response To Transforming Growth Factor Beta Stimulus Posttranscriptional Regulation Of Gene Expression Secretion Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Response To Transforming Growth Factor Beta Regulation Of Protein Catabolic Process JNK Cascade Response To Organic Substance
Tagcloud ?		15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta	adjustments associates confounders continued cubic cv geriatric gnri handgrip hemodialysis hospitalization hospitalizations malnutrition mhd mis nutritional observational outpatients qol scales sf sf36 spline sua tertile trends upcoming uric y
Tagcloud (Difference) ?		15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta	adjustments associates confounders continued cubic cv geriatric gnri handgrip hemodialysis hospitalization hospitalizations malnutrition mhd mis nutritional observational outpatients qol scales sf sf36 spline sua tertile trends upcoming uric y
Tagcloud (Intersection) ?