BSG and PPIA

Number of citations of the paper that reports this interaction (PMID 11943775)
54

Data Source:
HPRD (two hybrid, in vivo)

		BSG	PPIA
Gene Name		basigin (Ok blood group)	peptidylprolyl isomerase A (cyclophilin A)
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Sarcolemma Melanosome Membrane Raft Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Nucleus Cytosol Focal Adhesion Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Mannose Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Peptide Binding Poly(A) RNA Binding Virion Binding Unfolded Protein Binding
	Biological Process	Pyruvate Metabolic Process Cell Surface Receptor Signaling Pathway Embryo Implantation Blood Coagulation Extracellular Matrix Disassembly Extracellular Matrix Organization Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Cellular Metabolic Process Small Molecule Metabolic Process Response To Mercury Ion Decidualization Leukocyte Migration Response To CAMP Protein Targeting To Plasma Membrane	Protein Peptidyl-prolyl Isomerization Platelet Degranulation RNA-dependent DNA Replication Protein Folding Blood Coagulation Viral Process Viral Life Cycle Uncoating Of Virus Virion Assembly Viral Release From Host Cell Platelet Activation Entry Into Host Cell Lipid Particle Organization Regulation Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Leukocyte Migration Establishment Of Integrated Proviral Latency
Pathways		Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle Integrin cell surface interactions The citric acid (TCA) cycle and respiratory electron transport Degradation of the extracellular matrix Basigin interactions Cell surface interactions at the vascular wall	HIV Infection Host Interactions of HIV factors Integration of provirus Platelet degranulation Basigin interactions Late Phase of HIV Life Cycle Cell surface interactions at the vascular wall Uncoating of the HIV Virion Early Phase of HIV Life Cycle Reverse Transcription of HIV RNA Assembly Of The HIV Virion HIV Life Cycle Budding and maturation of HIV virion Response to elevated platelet cytosolic Ca2+ Minus-strand DNA synthesis Platelet activation, signaling and aggregation Binding and entry of HIV virion Plus-strand DNA synthesis APOBEC3G mediated resistance to HIV-1 infection
Drugs			Cyclosporine L-Proline (3r)-1-Acetyl-3-Methylpiperidine Ethyl Oxo(Piperidin-1-Yl)Acetate (3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl-
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CAV1 HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A3 SLC2A4	22 interactors: APP BSG CD99 ITK JAK2 LIG4 LNX1 NOTCH3 PAXIP1 PRLR PRR13 PRSS23 PTPRN RB1 S100A8 SRPK1 SRPK2 SUPT5H TCF4 TERT USP4 YY1
Entrez ID		682	5478
HPRD ID		00176	00457
Ensembl ID		ENSG00000172270	ENSG00000196262
Uniprot IDs		P35613 Q54A51	P62937 Q567Q0
PDB IDs		3B5H 3I84 3I85 3QQN 3QR2	1AK4 1AWQ 1AWR 1AWS 1AWT 1AWU 1AWV 1BCK 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1FGL 1M63 1M9C 1M9D 1M9E 1M9F 1M9X 1M9Y 1MF8 1MIK 1NMK 1OCA 1RMH 1VBS 1VBT 1W8L 1W8M 1W8V 1YND 1ZKF 2ALF 2CPL 2CYH 2RMA 2RMB 2X25 2X2A 2X2C 2X2D 2XGY 3CYH 3CYS 3K0M 3K0N 3K0O 3K0P 3K0Q 3K0R 3ODI 3ODL 3RDD 4CYH 5CYH
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Migration Cell Motility Lactate Transmembrane Transport Plasma Membrane Lactate Transport Lactate Transport Locomotion Movement Of Cell Or Subcellular Component Negative Regulation Of JAK-STAT Cascade Immune System Process Response To Stress Membrane Organization Protein Localization To Membrane Amylopectin Biosynthetic Process Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Uncoating Of Virus Mevalonate Transport Behavioral Response To Nutrient Protein Peptidyl-prolyl Isomerization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Localization Regulation Of JAK-STAT Cascade Nitric Oxide Homeostasis Cellular Response To Oxygen Levels Transport Pyruvate Metabolic Process Monocarboxylic Acid Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Viral Release From Host Cell Viral Process Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Protein Localization To Plasma Membrane Regulation Of Secretion Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Protein Localization To Plasma Membrane Raft Positive Regulation Of Metalloenzyme Activity Caveola Assembly Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway	Chromosome Organization RNA Metabolic Process Activation Of JAK2 Kinase Activity Cellular Metabolic Process Positive Regulation Of Gene Expression Immune System Process RNA Processing Cell Differentiation Positive Regulation Of Metabolic Process Response To Stress Gene Expression Regulation Of Gene Expression Cellular Response To Stimulus Activation Of Janus Kinase Activity Neuron Apoptotic Process Organ Development Regulation Of RNA Metabolic Process DNA Metabolic Process Neuron Death Chromatin Organization Organelle Organization MRNA Processing Nucleobase-containing Compound Metabolic Process Positive Regulation Of Viral Process Response To Stimulus Developmental Process Protein Metabolic Process Positive Regulation Of Peptide Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Innate Immune Response Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Anatomical Structure Development System Development Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Cellular Nitrogen Compound Metabolic Process Immune Response MRNA Metabolic Process Leukocyte Aggregation Positive Regulation Of Proteolysis Cellular Component Assembly Chromatin Modification Leukocyte Cell-cell Adhesion Positive Regulation Of Viral Genome Replication Regulation Of Sequence-specific DNA Binding Transcription Factor Activity JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Homotypic Cell-cell Adhesion Response To Organic Substance
Tagcloud ?		15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta	ape1 apparently beetroot breaks cdkn2a consumed defenses differing formulations gexp gss hdls ho1 homeostatic il6 interindividual investigates occasions postprandial ptgs2 saturated scope sirt socs3 strand stratified ucp2 unsaturated volunteers
Tagcloud (Difference) ?		15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta	ape1 apparently beetroot breaks cdkn2a consumed defenses differing formulations gexp gss hdls ho1 homeostatic il6 interindividual investigates occasions postprandial ptgs2 saturated scope sirt socs3 strand stratified ucp2 unsaturated volunteers
Tagcloud (Intersection) ?