NAPB and TAF1B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NAPB	TAF1B
Gene Name		N-ethylmaleimide-sensitive factor attachment protein, beta	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuolar Membrane SNARE Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Extracellular Vesicular Exosome RNA Polymerase I Core Factor Complex
	Molecular Function	Soluble NSF Attachment Protein Activity Syntaxin Binding	RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding Transcription Factor Recruiting Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding TBP-class Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport SNARE Complex Disassembly Membrane Fusion	Chromatin Silencing At RDNA RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		10 interactors: ARL6IP1 SNAP23 STX16 STX1A STX3 STX4 STX5 STX6 TAF1B TFEC	24 interactors: APP EP300 ESR1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MYC NAPB NEDD4 NEDD4L PGR RRN3 RXRA SRPK1 TAF1A TAF1C TAF1D TBP THAP7 TP53 TRB TRIM24 UBTF
Entrez ID		63908	9014
HPRD ID		17627	05363
Ensembl ID		ENSG00000125814	ENSG00000115750
Uniprot IDs		Q4G0M0 Q9H115	Q53T94
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Organization Membrane Docking Synaptic Vesicle Exocytosis Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Golgi Vesicle Transport Protein Localization Neurotransmitter Secretion Synaptic Vesicle Transport Establishment Of Localization In Cell Cellular Protein Localization Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Cellular Localization Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Retrograde Transport, Endosome To Golgi Golgi Ribbon Formation Positive Regulation Of Protein Localization To Cell Surface Golgi Organization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Synaptic Transmission Organelle Localization Regulation Of Protein Localization To Cell Surface Secretion By Cell Positive Regulation Of Protein Localization To Plasma Membrane Organelle Organization Synaptic Transmission Endosomal Transport Secretion Transport Long-term Synaptic Potentiation Regulation Of Protein Localization Regulation Of Protein Localization To Plasma Membrane Regulation Of Synaptic Transmission Positive Regulation Of Exocytosis Cell-cell Signaling Post-Golgi Vesicle-mediated Transport Endomembrane System Organization RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript	Negative Regulation Of Gene Expression DNA-templated Transcription, Initiation Chromatin Silencing At RDNA Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Transcription Initiation From RNA Polymerase I Promoter Negative Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase I Promoter Negative Regulation Of Gene Expression, Epigenetic Gene Expression Chromatin Silencing Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase I Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Silencing Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Termination Positive Regulation Of Transcription, DNA-templated Chromatin Organization Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Viral Process DNA Packaging Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Biosynthetic Process DNA Conformation Change
Tagcloud ?		abeta42 accordingly accumulations aggregates approved autophagy bioavailable enduring experimentally fda fiber fibers ibm inclusion lysosomal muscle myositis oligomers orally pathologically phenylbutyrate recapitulate reverses secretase sporadic urea vacuolated vacuolization virtually	analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1c tata tbp tumourigenesis ubf
Tagcloud (Difference) ?		abeta42 accordingly accumulations aggregates approved autophagy bioavailable enduring experimentally fda fiber fibers ibm inclusion lysosomal muscle myositis oligomers orally pathologically phenylbutyrate recapitulate reverses secretase sporadic urea vacuolated vacuolization virtually	analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1c tata tbp tumourigenesis ubf
Tagcloud (Intersection) ?