NAPB and SNAP23

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NAPB	SNAP23
Description		NSF attachment protein beta	synaptosome associated protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Glutamatergic Synapse	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Cilium Membrane Phagocytic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Synapse Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Protein Transport Vesicle-mediated Transport Synaptic Transmission, Glutamatergic SNARE Complex Disassembly	Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Membrane Fusion
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Factor VII activity ( 30642921)	Bipolar disorder ( 31043756)
Interacting Genes		32 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 DSCAM FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		63908	8773
HPRD ID		17627	03962
Ensembl ID		ENSG00000125814	ENSG00000092531
Uniprot IDs		A0A087WZQ7 Q9H115	A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion SNARE Binding Membrane Fusion Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Vesicle Organization Membrane Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Endomembrane System Synaptic Vesicle Membrane Organization Exocytosis Organelle Localization Vesicle-mediated Transport Secretion By Cell Secretion Establishment Of Protein Localization Membrane Syntaxin Binding Presynaptic Active Zone Membrane Protein Transport Intracellular Protein Transport Neurotransmitter Transport Specific Granule Synaptic Vesicle Membrane Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Cellular Localization Establishment Of Localization In Cell Organelle Organization Positive Regulation Of Exocytosis Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Neuron Projection Calcium-ion Regulated Exocytosis Intracellular Transport Intracellular Protein Localization Arachidonate Binding Cornified Envelope Assembly Spontaneous Neurotransmitter Secretion Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Regulated Secretory Pathway Chromaffin Granule Membrane	SNARE Complex SNAP Receptor Activity Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion SNARE Binding Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Protein Transport Establishment Of Protein Localization Vesicle-mediated Transport Secretion By Cell Vesicle Organization Secretion Membrane Organization Establishment Of Localization In Cell Intracellular Protein Localization SNARE Complex Assembly Syntaxin Binding Organelle Localization Intracellular Protein Transport Regulation Of Exocytosis Cellular Localization Intracellular Transport Regulation Of Synaptic Vesicle Priming Regulation Of Vesicle-mediated Transport Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Secretion By Cell Regulated Exocytosis Calcium-ion Regulated Exocytosis Endomembrane System Regulation Of Secretion Zymogen Granule Membrane Phagocytic Vesicle Positive Regulation Of Exocytosis Neutrophil Degranulation Regulation Of Histamine Secretion By Mast Cell Vesicle-mediated Transport In Synapse Neuron Projection Recycling Endosome Membrane Secretory Granule Regulation Of Hormone Secretion Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Exocytosis Synaptic Vesicle Membrane
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