NAPB and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NAPB	ARL6IP1
Description		NSF attachment protein beta	ARL6 interacting reticulophagy regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Glutamatergic Synapse	Cytoplasm Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding	Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Protein Transport Vesicle-mediated Transport Synaptic Transmission, Glutamatergic SNARE Complex Disassembly	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Factor VII activity ( 30642921)	Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)
Interacting Genes		32 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 DSCAM FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139	78 interacting genes: ACSF2 AQP6 ARL4D ARL6 BCL2L13 C19orf18 CERT1 DIABLO DRC4 EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35H1 SLC61A1 SLC71A2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		63908	23204
HPRD ID		17627	09641
Ensembl ID		ENSG00000125814	ENSG00000170540
Uniprot IDs		A0A087WZQ7 Q9H115	Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion SNARE Binding Membrane Fusion Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Vesicle Organization Membrane Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Endomembrane System Synaptic Vesicle Membrane Organization Exocytosis Organelle Localization Vesicle-mediated Transport Secretion By Cell Secretion Establishment Of Protein Localization Membrane Syntaxin Binding Presynaptic Active Zone Membrane Protein Transport Intracellular Protein Transport Neurotransmitter Transport Specific Granule Synaptic Vesicle Membrane Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Cellular Localization Establishment Of Localization In Cell Organelle Organization Positive Regulation Of Exocytosis Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Neuron Projection Calcium-ion Regulated Exocytosis Intracellular Transport Intracellular Protein Localization Arachidonate Binding Cornified Envelope Assembly Spontaneous Neurotransmitter Secretion Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Regulated Secretory Pathway Chromaffin Granule Membrane	Lipid Binding Phosphatidylinositol Binding Cellular Localization Establishment Of Protein Localization Retromer Complex Intracellular Transport Protein Transport Membrane Establishment Of Localization In Cell Leptin Receptor Binding Localization Within Membrane Intracellular Protein Transport Early Endosome To Golgi Transport Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport Retrograde Transport, Endosome To Golgi Endosome Phosphatidylinositol-4-phosphate Binding Transferrin Receptor Binding Negative Regulation Of Early Endosome To Late Endosome Transport Endosomal Transport Endocytic Recycling Cytosolic Transport Early Endosome Membrane Phosphatidylinositol-3-phosphate Binding Protein Targeting To Golgi Apparatus Protein Binding Mitochondrial Matrix Early Endosome Retromer, Tubulation Complex Golgi Vesicle Budding Cargo Adaptor Activity Establishment Of Protein Localization To Plasma Membrane Insulin Receptor Binding Vesicle-mediated Transport Organelle Organization Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport Succinate Metabolic Process Lamellipodium Morphogenesis Epidermal Growth Factor Receptor Binding Vesicle Budding From Membrane Protein Localization To Membrane Vesicle Organization Positive Regulation Of Exocytosis Regulation Of Establishment Of Protein Localization Membrane Organization Golgi Cisterna Regulation Of Protein Localization
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