NAPB and STX1A

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		NAPB	STX1A
Gene Name		N-ethylmaleimide-sensitive factor attachment protein, beta	syntaxin 1A (brain)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuolar Membrane SNARE Complex Extracellular Vesicular Exosome	Extracellular Region Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane SNARE Complex Actomyosin Neuron Projection Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
	Molecular Function	Soluble NSF Attachment Protein Activity Syntaxin Binding	SNARE Binding Glycoprotein Binding SNAP Receptor Activity Protein Binding Myosin Binding Calcium Channel Inhibitor Activity Chloride Channel Inhibitor Activity Kinase Binding Protein Domain Specific Binding Protein Binding, Bridging Myosin Head/neck Binding ATP-dependent Protein Binding Protein Heterodimerization Activity Protein N-terminus Binding Calcium-dependent Protein Binding
	Biological Process	Intracellular Protein Transport SNARE Complex Disassembly Membrane Fusion	Positive Regulation Of Neurotransmitter Secretion Energy Reserve Metabolic Process Intracellular Protein Transport Synaptic Transmission Neurotransmitter Secretion Pathogenesis Response To Gravity Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Calcium Ion-dependent Exocytosis Synaptic Vesicle Fusion To Presynaptic Membrane Secretion By Cell Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Exocytosis Vesicle Docking Regulation Of Insulin Secretion Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways			Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Toxicity of botulinum toxin type C (BoNT/C) Norepinephrine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Peptide hormone metabolism Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Insulin processing Serotonin Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ARL6IP1 SNAP23 STX16 STX1A STX3 STX4 STX5 STX6 TAF1B TFEC	58 interactors: ABCC9 APBA1 ATP4B ATP6V1B1 CACNA1D CCSER2 CDK5 CFTR CPLX1 CSNK2A1 CSNK2A2 DAPK1 KCNB1 NAPA NAPB NSF PSMA3 RAB27A RIMS1 SCNN1A SCNN1B SCNN1G SDCBP SEPT2 SEPT5 SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A9 SNAP23 SNAP25 SNAP29 SNPH STX8 STXBP1 STXBP2 STXBP5 STXBP6 SUMO1P1 SYT1 SYT4 SYT7 SYTL4 TRDMT1 TXLNA TXLNB UNC13B VAMP1 VAMP2 VAMP5 VAMP7 VAMP8 VAPB VIM VPS11 VPS18
Entrez ID		63908	6804
HPRD ID		17627	01721
Ensembl ID		ENSG00000125814	ENSG00000106089
Uniprot IDs		Q4G0M0 Q9H115	A8MZ54 Q16623 Q75ME0
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Organization Membrane Docking Synaptic Vesicle Exocytosis Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Golgi Vesicle Transport Protein Localization Neurotransmitter Secretion Synaptic Vesicle Transport Establishment Of Localization In Cell Cellular Protein Localization Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Cellular Localization Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Retrograde Transport, Endosome To Golgi Golgi Ribbon Formation Positive Regulation Of Protein Localization To Cell Surface Golgi Organization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Synaptic Transmission Organelle Localization Regulation Of Protein Localization To Cell Surface Secretion By Cell Positive Regulation Of Protein Localization To Plasma Membrane Organelle Organization Synaptic Transmission Endosomal Transport Secretion Transport Long-term Synaptic Potentiation Regulation Of Protein Localization Regulation Of Protein Localization To Plasma Membrane Regulation Of Synaptic Transmission Positive Regulation Of Exocytosis Cell-cell Signaling Post-Golgi Vesicle-mediated Transport Endomembrane System Organization RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript	Exocytosis Secretion By Cell Neurotransmitter Transport Secretion Regulation Of Exocytosis Regulation Of Neurotransmitter Levels Transport Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Transmission Cell-cell Signaling Regulation Of Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Cellular Localization Positive Regulation Of Exocytosis Regulation Of Cellular Localization Membrane Fusion Glutamate Secretion Establishment Of Vesicle Localization Vesicle Localization Ion Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Amino Acid Transport Vesicle Docking Organelle Fusion Membrane Docking Establishment Of Organelle Localization Membrane Organization Acid Secretion Vesicle Organization Positive Regulation Of Secretion Organelle Localization Protein Localization Monovalent Inorganic Cation Transport Anion Transport Dicarboxylic Acid Transport Regulated Secretory Pathway Metal Ion Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transport Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Sodium Ion Transport Organic Anion Transport
Tagcloud ?		abeta42 accordingly accumulations aggregates approved autophagy bioavailable enduring experimentally fda fiber fibers ibm inclusion lysosomal muscle myositis oligomers orally pathologically phenylbutyrate recapitulate reverses secretase sporadic urea vacuolated vacuolization virtually	colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence
Tagcloud (Difference) ?		abeta42 accordingly accumulations aggregates approved autophagy bioavailable enduring experimentally fda fiber fibers ibm inclusion lysosomal muscle myositis oligomers orally pathologically phenylbutyrate recapitulate reverses secretase sporadic urea vacuolated vacuolization virtually	colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence
Tagcloud (Intersection) ?