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SRP14 and IL7R
Number of citations of the paper that reports this interaction (PMID
23151878
)
3
Data Source:
BioGRID
(unspecified method)
SRP14
IL7R
Gene Name
signal recognition particle 14kDa (homologous Alu RNA binding protein)
interleukin 7 receptor
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Signal Recognition Particle, Endoplasmic Reticulum Targeting
Cytosol
Intercellular Bridge
Extracellular Vesicular Exosome
Extracellular Region
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Molecular Function
RNA Binding
Protein Binding
7S RNA Binding
Endoplasmic Reticulum Signal Peptide Binding
Poly(A) RNA Binding
Antigen Binding
Interleukin-7 Receptor Activity
Protein Binding
Biological Process
Translation
Cotranslational Protein Targeting To Membrane
SRP-dependent Cotranslational Protein Targeting To Membrane
Gene Expression
Response To Drug
Cellular Protein Metabolic Process
Protein Targeting To ER
Regulation Of DNA Recombination
Cell Morphogenesis
Negative Regulation Of T Cell Mediated Cytotoxicity
Immunoglobulin Production
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Cell Growth
T Cell Differentiation
Positive Regulation Of T Cell Differentiation In Thymus
Interleukin-7-mediated Signaling Pathway
B Cell Proliferation
Lymph Node Development
Homeostasis Of Number Of Cells
Pathways
Translation
SRP-dependent cotranslational protein targeting to membrane
Signaling by Interleukins
Interleukin-7 signaling
Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Ewing sarcoma (
22327514
)
Obesity-related traits (
23251661
)
Multiple sclerosis (
21244703
19525953
21833088
)
Primary biliary cirrhosis (
23000144
21399635
)
Type 1 diabetes (
17554260
)
Ulcerative colitis (
21297633
)
Protein-Protein Interactions
4 interactors:
CALM1
IL7R
NSFL1C
SRP9
104 interactors:
ALYREF
CIRBP
CPSF1
CRLF2
DDX21
DDX39B
DDX3X
DDX5
DHX36
DHX9
EIF2AK2
ELAVL1
EMG1
FAU
FUS
FYN
G3BP1
GNB2L1
H1FX
HIST1H1C
HIST1H1E
HIST2H2BE
HNRNPA0
HNRNPA3
HNRNPAB
HNRNPC
HNRNPD
HNRNPDL
HNRNPH3
HNRNPL
HNRNPR
HNRNPU
HNRNPUL1
HNRNPUL2
IL2RG
IL7
ILF2
ILF3
JAK1
JAK3
KIT
LYN
MAP4
NCL
NONO
PABPC1
PABPC4
PABPN1
PIK3R1
PTBP1
PTK2B
PTMA
PURA
PURB
QKI
RAD21
RBM3
RBMX
RPL15
RPL18
RPL22
RPL29
RPL30
RPL31
RPL6
RPL7
RPL8
RPS20
RPS3
RPSA
RRAGA
RSL1D1
SAFB
SF1
SF3A1
SF3B1
SNRNP70
SNRPA
SNRPB
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SNRPG
SRP14
SRP9
SRSF3
SRSF9
SSB
STAT3
STAT5A
STAT5B
SYNCRIP
TOE1
TOP1
TSLP
U2AF1
U2AF2
YBX1
YBX3
YWHAE
YWHAG
ZNF787
Entrez ID
6727
3575
HPRD ID
02831
00893
Ensembl ID
ENSG00000140319
ENSG00000168685
Uniprot IDs
P37108
D6RGV2
D9N160
P16871
PDB IDs
1E8O
1E8S
1RY1
3DI2
3DI3
3UP1
Enriched GO Terms of Interacting Partners
?
Membrane Organization
Interleukin-7-mediated Signaling Pathway
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Negative Regulation Of Translational Elongation
Regulation Of High Voltage-gated Calcium Channel Activity
Negative Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Detection Of Calcium Ion
Nuclear Envelope Reassembly
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Phosphoprotein Phosphatase Activity
Negative Regulation Of T Cell Mediated Immunity
Lymph Node Development
Positive Regulation Of T Cell Differentiation In Thymus
Positive Regulation Of Peptidyl-threonine Phosphorylation
Positive Regulation Of Protein Autophosphorylation
Positive Regulation Of Nitric-oxide Synthase Activity
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Glycogen Catabolic Process
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Cation Channel Activity
Polysaccharide Catabolic Process
Positive Regulation Of Monooxygenase Activity
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Positive Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Rhodopsin Mediated Signaling Pathway
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Activation Of Adenylate Cyclase Activity
Nitric Oxide Metabolic Process
Cell Activation
Regulation Of Protein Autophosphorylation
Reactive Nitrogen Species Metabolic Process
Rhodopsin Mediated Signaling Pathway
Cellular Carbohydrate Catabolic Process
Regulation Of T Cell Differentiation In Thymus
Positive Regulation Of Phosphatase Activity
Response To Corticosterone
Positive Regulation Of Cation Channel Activity
Response To Amphetamine
Positive Regulation Of Adenylate Cyclase Activity
Regulation Of Phosphoprotein Phosphatase Activity
Negative Regulation Of Adaptive Immune Response
Response To Mineralocorticoid
Regulation Of Nitric-oxide Synthase Activity
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Processing
RNA Splicing
MRNA Processing
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Viral Process
RNA Biosynthetic Process
SRP-dependent Cotranslational Protein Targeting To Membrane
Termination Of RNA Polymerase II Transcription
Cotranslational Protein Targeting To Membrane
Protein Targeting To ER
Establishment Of Protein Localization To Endoplasmic Reticulum
Cellular Macromolecule Biosynthetic Process
Regulation Of MRNA Stability
Regulation Of RNA Stability
Macromolecule Biosynthetic Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Protein Localization To Endoplasmic Reticulum
Viral Life Cycle
Cytoplasmic Transport
Posttranscriptional Regulation Of Gene Expression
MRNA Stabilization
RNA 3'-end Processing
MRNA 3'-end Processing
RNA Catabolic Process
Viral Transcription
Cellular Metabolic Process
Protein Targeting To Membrane
DNA-templated Transcription, Termination
Protein Targeting
Nuclear-transcribed MRNA Catabolic Process
Establishment Of Protein Localization To Organelle
MRNA Catabolic Process
Ribonucleoprotein Complex Assembly
Regulation Of Translation
Ribonucleoprotein Complex Biogenesis
Biosynthetic Process
Protein Localization To Organelle
Translational Termination
Establishment Of Protein Localization To Membrane
Intracellular Transport
Translational Elongation
Tagcloud
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Intersection)
?