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SP4 and SERF2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SP4
SERF2
Gene Name
Sp4 transcription factor
small EDRK-rich factor 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Microtubule Cytoskeleton
Intercellular Bridge
Nucleus
Cytosol
Molecular Function
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
DNA Binding
Transcription Coactivator Activity
Metal Ion Binding
Molecular_function
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Regulation Of Heart Contraction
Biological_process
Pathways
Drugs
Diseases
GWAS
Major depressive disorder (
20125088
)
Major depressive disorder (broad) (
20038947
)
Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) (
23103227
)
Protein-Protein Interactions
14 interactors:
ADAM15
ATXN7L1
CIB3
COL8A1
E2F1
FOXP2
LMO3
NKX3-1
NRF1
POU2F1
PRR20A
SERF2
SP1
ZBTB7A
15 interactors:
BOLL
CHD3
DAB1
GC
KRTAP10-3
MDFI
NELFCD
PSMA3
PSME3
QKI
RBPMS
RHOXF2
SP4
THAP1
UPF2
Entrez ID
6671
10169
HPRD ID
02764
05447
Ensembl ID
ENSG00000105866
Uniprot IDs
Q02446
P84101
PDB IDs
Enriched GO Terms of Interacting Partners
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Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Receptor Binding
Organ Development
RNA Metabolic Process
Camera-type Eye Development
Multicellular Organismal Development
Gene Expression
Eye Development
Transcription From RNA Polymerase II Promoter
Camera-type Eye Morphogenesis
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Tissue Development
Organ Morphogenesis
Eye Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Formation Involved In Morphogenesis
Developmental Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
System Development
Negative Regulation Of RNA Biosynthetic Process
Sensory Organ Development
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Respiratory System Development
Response To Hypoxia
Regulation Of Gene Expression
Anatomical Structure Development
Negative Regulation Of Protein Binding
Regulation Of Nitrogen Compound Metabolic Process
Anatomical Structure Morphogenesis
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Collagen Catabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Cardiovascular System Development
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
Positive Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Transferase Activity
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Regulation Of Gene Expression
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Transferase Activity
Negative Regulation Of Ubiquitin-protein Transferase Activity
Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
Regulation Of Cellular Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
RNA Metabolic Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cerebellum Structural Organization
3'-UTR-mediated MRNA Destabilization
Glucosylceramide Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
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