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SERF2 and GC
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SERF2
GC
Gene Name
small EDRK-rich factor 2
group-specific component (vitamin D binding protein)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Extracellular Region
Extracellular Space
Cytosol
Lysosomal Lumen
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Molecular_function
Actin Binding
Vitamin D Binding
Vitamin Transporter Activity
Calcidiol Binding
Biological Process
Biological_process
Steroid Metabolic Process
Vitamin D Metabolic Process
Small Molecule Metabolic Process
Vitamin Transport
Pathways
Metabolism of lipids and lipoproteins
Metabolism of steroid hormones and vitamin D
Vitamin D (calciferol) metabolism
Drugs
Diseases
GWAS
Metabolite levels (
22916037
)
Non-alcoholic fatty liver disease histology (other) (
23213074
)
Vitamin D insufficiency (
20541252
)
Vitamin D levels (
22673963
20418485
)
Protein-Protein Interactions
15 interactors:
BOLL
CHD3
DAB1
GC
KRTAP10-3
MDFI
NELFCD
PSMA3
PSME3
QKI
RBPMS
RHOXF2
SP4
THAP1
UPF2
12 interactors:
ACTA1
ACTA2
ACTC1
C3
CCND3
CDC73
CUBN
GRB2
LRIF1
LRP2
PIK3R3
SERF2
Entrez ID
10169
2638
HPRD ID
05447
00749
Ensembl ID
ENSG00000145321
Uniprot IDs
P84101
P02774
PDB IDs
1J78
1J7E
1KW2
1KXP
1LOT
1MA9
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
Positive Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Transferase Activity
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Regulation Of Gene Expression
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Transferase Activity
Negative Regulation Of Ubiquitin-protein Transferase Activity
Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
Regulation Of Cellular Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
RNA Metabolic Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cerebellum Structural Organization
3'-UTR-mediated MRNA Destabilization
Glucosylceramide Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Skeletal Muscle Thin Filament Assembly
Skeletal Myofibril Assembly
Vitamin D Metabolic Process
Actin-myosin Filament Sliding
Muscle Filament Sliding
Muscle Contraction
Actin-mediated Cell Contraction
Muscle System Process
Actin Filament-based Movement
Receptor-mediated Endocytosis
Myofibril Assembly
Tissue Development
Skeletal Muscle Fiber Adaptation
Positive Regulation Of Type IIa Hypersensitivity
Cell Development
Response To External Stimulus
Anatomical Structure Formation Involved In Morphogenesis
Actomyosin Structure Organization
Vitamin Metabolic Process
Positive Regulation Of Activation Of Membrane Attack Complex
Insulin Receptor Signaling Pathway
Striated Muscle Cell Development
Lipid Metabolic Process
Glomerular Mesangial Cell Development
Regulation Of Phosphorylation
Muscle Cell Development
Cobalamin Transport
Mesangial Cell Development
Positive Regulation Of Hypersensitivity
Endocytosis
Renal Interstitial Fibroblast Development
Positive Regulation Of Apoptotic Cell Clearance
Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Histone H2B Ubiquitination
Skeletal Muscle Adaptation
Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Cellular Response To Insulin Stimulus
Tagcloud
?
absent
agglutinin
bcr
bm
centers
centroblasts
centrocytes
chimeric
clusters
fdc
follicles
follicular
gcs
germinal
grafts
hosts
humoral
lt
ltbeta
ltbetar
lymphotoxin
networks
peanut
pna
radioresistant
reciprocal
reconstituted
splenic
tnfrp55
Tagcloud (Difference)
?
absent
agglutinin
bcr
bm
centers
centroblasts
centrocytes
chimeric
clusters
fdc
follicles
follicular
gcs
germinal
grafts
hosts
humoral
lt
ltbeta
ltbetar
lymphotoxin
networks
peanut
pna
radioresistant
reciprocal
reconstituted
splenic
tnfrp55
Tagcloud (Intersection)
?