SP4 and PRR20A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SP4	PRR20A
Gene Name		Sp4 transcription factor	proline rich 20A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Transcription Coactivator Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Heart Contraction
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 20125088) Major depressive disorder (broad) ( 20038947) Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227)
Protein-Protein Interactions		14 interactors: ADAM15 ATXN7L1 CIB3 COL8A1 E2F1 FOXP2 LMO3 NKX3-1 NRF1 POU2F1 PRR20A SERF2 SP1 ZBTB7A	24 interactors: ATXN1 C1orf94 DAB1 DAZAP2 FAM168A FOXP3 GATA2 NAA38 NCK2 NEDD9 PITX1 POGZ RBFOX1 RBPMS ROR2 SELV SIAH1 SOX5 SP4 THAP1 TOLLIP VAC14 ZC3H10 ZNF488
Entrez ID		6671	122183
HPRD ID		02764	13445
Ensembl ID		ENSG00000105866	ENSG00000204919
Uniprot IDs		Q02446	P86478 P86479 P86480 P86481 P86496
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Receptor Binding Organ Development RNA Metabolic Process Camera-type Eye Development Multicellular Organismal Development Gene Expression Eye Development Transcription From RNA Polymerase II Promoter Camera-type Eye Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Tissue Development Organ Morphogenesis Eye Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Developmental Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription System Development Negative Regulation Of RNA Biosynthetic Process Sensory Organ Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Respiratory System Development Response To Hypoxia Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Protein Binding Regulation Of Nitrogen Compound Metabolic Process Anatomical Structure Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Collagen Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Cardiovascular System Development	Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Cellular Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Gene Expression Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cartilage Development Positive Regulation Of Cell Differentiation Anatomical Structure Development Regulation Of Histone Acetylation System Development Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Positive Regulation Of Peripheral T Cell Tolerance Induction Pituitary Gland Development Central Nervous System Development Connective Tissue Development Ventral Spinal Cord Development Generation Of Neurons Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cerebellum Structural Organization Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Eosinophil Fate Commitment Cell Fate Commitment Neurogenesis Nervous System Development Developmental Process Negative Regulation Of Nucleic Acid-templated Transcription Neuron Differentiation Regulation Of Glial Cell Differentiation Negative Regulation Of RNA Biosynthetic Process
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